ABSTRACT
Eleven compounds isolated from the heartwood of Mansonia gagei were tested for their antifungal activities against Cladosporium cucumerinum and Candida albicans, as well as for their larvicidal activities against Aedes aegypti and radical scavenging properties in a DPPH assay. Mansonone C (4) was found to be the most interesting compound with antifungal activities against Cladosporium cucumerinum and Candida albicans as well as for its larvicidal properties against Aedes aegypti. Mansonone E (5) was active against Cladosporium cucumerinum and Candida albicans. Two coumarin derivatives, mansorin A (1) and mansorin B (2) were also found to be active against Cladosporium cucumerinum, while mansonone N (9) was the only isolated product to show radical scavenging properties.
Subject(s)
Antifungal Agents/pharmacology , Antioxidants/pharmacology , Insecticides/pharmacology , Malvaceae , Phytotherapy , Plant Extracts/pharmacology , Aedes/drug effects , Animals , Antifungal Agents/administration & dosage , Antifungal Agents/therapeutic use , Antioxidants/administration & dosage , Antioxidants/therapeutic use , Biphenyl Compounds , Candida albicans/drug effects , Cladosporium/drug effects , Free Radical Scavengers/administration & dosage , Free Radical Scavengers/pharmacology , Free Radical Scavengers/therapeutic use , Insecticides/administration & dosage , Larva/drug effects , Microbial Sensitivity Tests , Picrates , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , TreesABSTRACT
The CHCl3 extract of the whole plant of Arundo donax yielded N-(4'-bromophenyl)-2,2-diphenylacetanilide [1]. The structure was determined on the basis of chemical, spectroscopic, and X-ray crystallographic data. Compound 1 has not been previously reported as a natural product and showed inhibition of feeding for boll weevils.
Subject(s)
Acetanilides/chemistry , Benzhydryl Compounds/chemistry , Insecta , Insecticides/chemistry , Plants/chemistry , Acetanilides/pharmacology , Animals , Benzhydryl Compounds/pharmacology , Crystallography, X-Ray , Feeding Behavior/drug effects , Insecticides/pharmacology , Magnetic Resonance Spectroscopy , ThailandABSTRACT
The chloroform extracts of the roots and leaves of Sarracenia flava showed antitumor activity against lymphocytic leukemia P-388. Lupeol was identified as one constituent responsible for this activity. Beta-Sitosterol and alpha-amyrin were isolated from the hexane extract of the roots.
