1.
J Biochem Toxicol
; 8(2): 107-10, 1993 Jun.
Article
in English
| MEDLINE
| ID: mdl-8394937
ABSTRACT
The reaction of phosgene with nitrone spin traps was investigated using electron paramagnetic resonance (EPR)/spin trapping techniques. Evidence for the intermediacy of a carbamoyl monochloride intermediate was obtained. Isotopic substitution of 13C-phosgene was employed to verify the hyperfine coupling constant assignments. The implications of these observations on pulmonary damage caused by inhalation of phosgene are mentioned.