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4.
Vopr Med Khim ; 33(5): 122-4, 1987.
Article in Russian | MEDLINE | ID: mdl-3318106

ABSTRACT

Intramuscular administration of trypsin and kallikrein (andecaline) into rats contributed to more favourable development of acute traumatic pancreatitis. Trypsin and andecaline prevented the activation of proteinases in blood serum and pancreas and promoted an increase in content of trypsin inhibitor in blood serum. The proteinases efficiency appears to depend on elevation of general resistance of the organism to the trauma.


Subject(s)
Kallikreins/therapeutic use , Pancreatitis/enzymology , Peptide Hydrolases/blood , Protease Inhibitors/blood , Trypsin/therapeutic use , Acute Disease , Animals , Enzyme Activation , Hydrolysis , Pancreatitis/drug therapy , Rats , Rats, Inbred Strains
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