[The influence of soybean proteins on melanoma B-16 growth versus free-radical mechanisms in tumor-bearing animals].

The study deals with antitumor action of soybean proteins as natural bio-mediators for alleviating side-effects of chemotherapy. The influence of soybean proteins on antibody formation and free-radical mechanisms in blood serum was assessed in melanoma B-16-bearing mice. Use of soybean proteins was followed by a 65% rise in inhibition of tumor growth and an 1.4-fold increase in survival time. In particular, an enhanced level of antibody formation cells in the spleen and normalization of oxidative processes in blood serum were reported.

[Peroxidation of serum lipids in patients with breast cancer]. / Perekisnoe okislenie lipidov syvorotki krovi bol'nykh rakom molochnoi zhelezy.

Parameters of chemiluminescence of lipid peroxidation (LP), induced by hydrogen peroxide in the blood serum of oncology patients (n = 60), were examined in the process of their combined therapy. During the dynamic observations, complete correlations were found between the peculiarities of manifestations and of the clinical course of the tumor process, the level of free-radical LP and the antioxidants of blood serum. A comprehensive assessment of all mentioned indices can be used to monitor the efficiency of a conducted therapy.