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1.
Diagn Cytopathol ; 49(4): 533-539, 2021 Apr.
Article in English | MEDLINE | ID: mdl-33369154

ABSTRACT

OBJECTIVE: Sternocleidomastoid tumor of infancy (SCMI) is a rare, benign self-limiting condition which occurs in the perinatal period. The goal of our study is to highlight clinicoradiological and cytopathological findings in these cases. MATERIAL AND METHODS: A study was done at a tertiary level hospital, from January 2016 to December 2019. Thirteen cases were studied, out of which 11 were clinically suspected cases of SCMI tumor and two cases were clinically suspected as cervical lymph node tuberculosis which were finally diagnosed as SCMI on fine needle aspiration cytology (FNAC) evaluation. Drs. N. K., S. Z., S. S. K., and S. R. independently reviewed the original diagnosis. Clinical, ultrasonographical, and cytopathological features are highlighted along with follow-up of the cases. RESULTS: There were a total of 13 cases, out of which 11 cases were neonates and two cases were more than 1 month of age (2 months and 2.5 months). Male: female ratio was 10:3 and swelling was present more commonly on the right side of the neck. Ultrasonography predominantly showed non-cystic, bulky, and heterogenous echotexture of the sternocleidomastoid muscle. Smears were moderately cellular showing mainly singly scattered oval to spindle shaped fibroblasts along with degenerating and regenerating muscle fibers. CONCLUSION: FNAC along with adequate clinic-radiological correlation aids in early and reliable diagnosis and can help curtail complications.


Subject(s)
Fibroma/pathology , Head and Neck Neoplasms/pathology , Infant, Newborn, Diseases/pathology , Neck Muscles/pathology , Biopsy, Fine-Needle/methods , Biopsy, Fine-Needle/standards , Diagnosis, Differential , Female , Fibroblasts/pathology , Fibroma/diagnostic imaging , Head and Neck Neoplasms/diagnostic imaging , Humans , Infant , Infant, Newborn , Infant, Newborn, Diseases/diagnostic imaging , Male , Muscle Fibers, Skeletal/pathology , Neck Muscles/diagnostic imaging , Ultrasonography/methods
2.
J Cytol ; 29(1): 83-5, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22438629

ABSTRACT

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy is a rare disease involving the lymph nodes. Extranodal RDD involving the thyroid is extremely rare. So far, six cases of RDD involving thyroid have been reported in the literature; all have occurred in females with a mean age of 56.3 years. Clinically, radiologically and cytologically, all the cases were initially diagnosed as thyroid malignancies with lymph nodal metastasis. The final diagnosis was made histologically only after total thyroidectomy. We herein, present a seventh case of RDD involving the thyroid in a 15-year-old female, diagnosed first on fine needle aspiration cytology (FNAC). We conclude that FNAC is a useful diagnostic procedure for RDD involving thyroid; it can avoid an unnecessary thyroidectomy.

3.
J Clin Neonatol ; 1(3): 157-9, 2012 Jul.
Article in English | MEDLINE | ID: mdl-24027716

ABSTRACT

Potter's sequence is a rare fatal disorder that occurs in sporadic and autosomal recessive forms with an incidence of 1 in 4000 births. Babies born with this condition are either still born or die very early within the neonatal period. We report a case of Potter's sequence with the typical physical findings and histological findings.

7.
J Cytol ; 27(3): 86-90, 2010 Jul.
Article in English | MEDLINE | ID: mdl-21187882

ABSTRACT

BACKGROUND: Rapid diagnosis of surgically removed specimens has created many controversies and a single completely reliable method has not yet been developed. Histopathology of a paraffin section remains the ultimate gold standard in tissue diagnosis. Frozen section is routinely used by the surgical pathology laboratories for intraoperative diagnosis. The use of either frozen section or cytological examination alone has an acceptable rate (93-97%) of correct diagnosis, with regard to interpretation of benign versus malignant. AIM: To evaluate the utility of scrape cytology for the rapid diagnosis of surgically removed tumors and its utilisation for learning cytopathology. MATERIALS AND METHODS: 75 surgically removed specimens from various organs and systems were studied. Scrapings were taken from each specimen before formalin fixation and stained by modified rapid Papanicolaou staining. RESULTS: Of the 75 cases studied, 73 could be correctly differentiated into benign and malignant tumors, with an accuracy rate of 97.3%. CONCLUSIONS: Intraoperative scrape cytology is useful for intraoperative diagnosis of tumor, where facilities for frozen section are not available. The skill and expertise developed by routinely practicing intraoperative cytology can be applied to the interpretation of fine needle aspirate smears. Thus, apart from its diagnostic role, intraoperative cytology can become a very useful learning tool in the field of cytopathology.

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