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Biosci Biotechnol Biochem ; 75(1): 181-4, 2011.
Article in English | MEDLINE | ID: mdl-21228470

ABSTRACT

Five carboxin-resistant mutants from Aspergillus oryzae were characterized by the sensitivities of their mycelial growth and succinate dehydrogenase (SDH) activity to carboxin and three related fungicides. Despite a significant resistance to carboxin, exhibited by all the mutants, their patterns of sensitivity to the other fungicides was distinct. This provides clues to the molecular interaction between SDH and these fungicides.


Subject(s)
Aspergillus oryzae/drug effects , Aspergillus oryzae/genetics , Carboxin/toxicity , Drug Resistance, Fungal/genetics , Fungicides, Industrial/toxicity , Mutation , Aspergillus oryzae/enzymology , Mycelium/drug effects , Mycelium/enzymology , Mycelium/genetics , Succinate Dehydrogenase/metabolism
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