ABSTRACT
This paper describes the clinical case - anterior myocardial infarction after blunt chest trauma in a 25-year-old man.
Subject(s)
Electrocardiography , Myocardial Infarction/etiology , Thoracic Injuries/complications , Wounds, Nonpenetrating/complications , Adult , Coronary Angiography , Diagnosis, Differential , Exercise Test , Humans , Male , Myocardial Infarction/diagnosis , Thoracic Injuries/diagnosis , Tomography, Emission-Computed , Wounds, Nonpenetrating/diagnosisABSTRACT
AIM: To compare antianginal and anti-ischemic efficiency and tolerance of two forms of isosorbide dinitrate--cardiket-retard 120 mg and cardiket-retard 40 mg in IHD patients with stable effort angina. MATERIAL AND METHODS: The study included 18 IHD patients with stable angina of functional class II (5 patients) and III (13 patients). The trial was open cross-over. The treatment with both the forms lasted 1 month. Frequency of anginal attacks and exercise tolerance by veloergometry data were assessed. RESULTS: A significant decrease in the number of anginal attacks and greater exercise tolerance was recorded in cardiket 120 mg intake once a day. Both forms were well tolerated, serious side effects were absent. CONCLUSION: Comparison of the two isosorbide dinitrate dosage forms--cardiket 120 mg once a day and cardiket 40 mg 3 times a day--showed that the former is superior by clinical efficiency.
Subject(s)
Angina Pectoris/drug therapy , Isosorbide Dinitrate/therapeutic use , Myocardial Ischemia/drug therapy , Vasodilator Agents/therapeutic use , Adult , Aged , Angina Pectoris/physiopathology , Data Interpretation, Statistical , Delayed-Action Preparations , Electrocardiography , Exercise Test , Female , Hemodynamics , Humans , Isosorbide Dinitrate/adverse effects , Male , Middle Aged , Myocardial Ischemia/physiopathology , Vasodilator Agents/adverse effectsABSTRACT
The diagnostic value of 24-hour ECG monitoring was assessed in 81 patients with stable angina of effort (functional classes II-IV) and 8 spontaneously-anginal patients. The pattern and frequency of transitory ST displacements, and their distribution by the hours of the day are reviewed. The results of 24-hour ECG monitoring are compared with clinical, bicycle-ergometric and coronaroangiographic findings. Spontaneously anginal patients showed peculiar episodes of transitory ischemia, with typically elevated ST, shorter duration and the occurrence mostly during the night and morning hours; 2/3 of such episodes were painless. High diagnostic value of the method for the assessment of the efficacy of anti-anginal drugs is demonstrated.
