ABSTRACT
Lipid composition of exhaled air condensate (EAC) was assessed by thin layer chromatography in patients with pneumonia and normal subjects. In parallel with this, diene conjugates and diene ketones were assessed by spectrophotometry. Berhan's principle was for the first time used for noninvasive obtaining of EAC from each lung separately. Decreased percentage of phospholipids and increased level of free fatty acids in EAC of patients with massive pneumonia may be an evidence of disordered pulmonary surfactant, and an increase of the intermediate products of lipid peroxidation indicate the cause of these changes.
Subject(s)
Breath Tests , Lipids/analysis , Pneumonia/metabolism , Chromatography, Thin Layer , Humans , Lipid Peroxidation , Lipid Peroxides/analysis , Male , Reference ValuesABSTRACT
The data of the immunological anamnesis and the results of studying cellular and humoral immunity as well as phagocytic activity of phagocytes were compared in 260 patients with acute pneumonia and 100 normal persons. The method of nonuniform successive recognition was used to study the prognostic value of anamnestically detectable factors at risk for immune deficiency. The diagnostic tables were elaborated in order to predict immune deficiency and derangements of some components of immunogenesis in normal persons and patients afflicted with pneumonia. The tables make it possible to differentiate between initial immunosuppression and secondary one provoked by the infectious process itself.
Subject(s)
Immunologic Deficiency Syndromes/diagnosis , Pneumonia/complications , Acute Disease , Adult , Antibody Formation/immunology , Diagnosis, Differential , Female , Humans , Immunity, Cellular/immunology , Immunologic Deficiency Syndromes/etiology , Immunologic Deficiency Syndromes/immunology , Male , Middle Aged , Pneumonia/immunology , PrognosisABSTRACT
Content of alpha 1-antitrypsin and alpha 2-macroglobulin was studied in blood serum of patients with acute and chronic forms of pneumonia. Within the first decade of the disease alpha 1-antitrypsin was more distinctly increased in the patients with chronic pneumonia. Stable elevation of alpha 1-antitrypsin correlated with long-term presence of the inflammation symptoms. Content of alpha 2-macroglobulin was slightly decreased during the disease.
