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1.
Lik Sprava ; (4): 8-10, 1999 Jun.
Article in Russian | MEDLINE | ID: mdl-10476630

ABSTRACT

Activity was studied of blood serum plasmic enzymes L-serine and L-threonine dehydrogenazes (SDG and ThDG) in 92 liquidators of aftermath of the Chernobyl atomic power plant breakdown, presenting with chronic non-calculous cholecystitis during the stage of moderately severe exacerbation with no clinical and laboratory and sonographic signs of affection of the liver. A quarter of the examinees demonstrated an increased activity of the enzymes under study, which fact is regarded by the authors as a preclinical sign of reactive hepatitis. Recommendations are given as to the outpatient registration and prophylactic management and therapy of those persons having taken part in the elimination of the effects of the Chernobyl accident, presenting with biliary pathologies.


Subject(s)
Alcohol Oxidoreductases/radiation effects , Cholecystitis/enzymology , L-Serine Dehydratase/radiation effects , Occupational Exposure/adverse effects , Power Plants , Radioactive Hazard Release , Threonine Dehydratase/radiation effects , Adult , Alcohol Oxidoreductases/blood , Chronic Disease , Humans , L-Serine Dehydratase/blood , Male , Middle Aged , Occupational Exposure/analysis , Threonine Dehydratase/blood , Ukraine
2.
Lik Sprava ; (5): 21-3, 1999 Jul.
Article in Russian | MEDLINE | ID: mdl-10822667

ABSTRACT

A retrospective analysis was performed of case histories and of results of sonographic investigations in liquidators of the Chernobyl accident suffering from chronic abnormalities of the biliary ducts. Patients with cholecystitis were studied for the biochemical composition of their bile. The incidence of the gallbladder disorders (chronic cholecystitis, angiocholitis, dyskinesias of the biliary ducts) has not changed much over the last 10 years having elapsed since the accident. The biochemical composition of bile was found to have been changed to a greater extent in the liquidators of the Chernobyl accident than it was in those having avoided danger of exposure to ionizing radiation. Mechanisms of origination of cholelithiasis are discussed on the basis of investigations designed to study biochemical properties of bile and findings secured with the aid of the ultrasound techniques.


Subject(s)
Biliary Tract Diseases/etiology , Power Plants , Radiation Injuries/complications , Radioactive Hazard Release , Adult , Bile/chemistry , Bile/radiation effects , Biliary Tract/diagnostic imaging , Biliary Tract Diseases/diagnostic imaging , Biliary Tract Diseases/metabolism , Chronic Disease , Female , Humans , Male , Middle Aged , Retrospective Studies , Time Factors , Ukraine , Ultrasonography
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