ABSTRACT
The long-term precision and stability of a new quality-control system for blood pH and gas measurements are compared to that of tonometered bicarbonate solutions and serum-based preparations. The new system, consisting of gas-equilibrated bicarbonate solutions in glass ampuls, is shown to be as stable as the serum-based preparation, and as reproducible as either of the other methods. The new system, offering three discrete sets of control values, has certain advantages in the simultaneous quality of pH, carbon dioxide tension, and oxygen tension measurements.
Subject(s)
Blood Gas Analysis , Hydrogen-Ion Concentration , Blood , Blood Gas Analysis/methods , Carbon Dioxide/blood , Evaluation Studies as Topic , Humans , Methods , Oxygen/blood , Partial Pressure , Quality ControlABSTRACT
We describe an evaluation of the in-use stability and short-term precision of a three-level ampuled quality-control system for monitoring pH, pCO2, and pO2 measurements on clinical blood-gas analyzers. In three hospital laboratories, 324 such ampuls were opened and allowed to stand with their contents exposed to atmospheric conditions for accurately timed intervals up to 240 s. Contents were then analyzed for pH, pCO2, and pO2. Student's t-test was used to evaluate the significance of differences observed in recoveries after time exposure. At a signifcance level of P less than or equal to 0.05, the only significant changes observed throughout the first minute of exposure were average pO2 increases of 180 Pa (1.4 mmHg) (+ 1.4%) and 230 Pa (1.7 mmHg) (+ 2.9%) at levels of 13.4 and 7.7 kPa kPa (101 and 58 mmHg), respectively. The ampuled system was found to be stable precise convenient, and suitable for use in the routine laboratory.
