[Solar phase effect on elasticity of the brachial artery and blood flow in humans].

Single and double examinations of normal males and females in the course of 11-year solar cycle with the use of oscillovasometry and occlusive plethysmography established a direct correlation between the effective diastolic radius of the brachial artery and solar activity characteristics on the day of examination, i.e. number of solar spots and intensity of radiation with the 10.7 cm wavelength. Other blood flow parameters demonstrated opposite correlations with the factors in males and females. As solar activity increased, females displayed linear decrements of arterial elasticity and regional peripheral resistance and growth of the volumetric blood flow velocity equally at rest and at the peak of post-occlusion reactive hyperemia. In males, the correlations had the reversed sign. Besides, males were noted to reduce venous reserve and venous outflow from antebrachial muscles proportionally to the increase of Wolf number. It is inferred that elevated solar activity may be responsible for impairment of the feeling of well-being of people with reduced cardiovascular reserve, particularly in space tight or at high altitudes in the absence of or under weak protection of the geomagnetic field and ozone layer.

[Liver regeneration at different stages of mononuclear infiltration induced by zymosan granules]. / Regeneratsiia pecheni v raznye periody mononuklearnoi infil'tratsii, indutsirovannoi zimozanovymi granulami.

The relationship between regeneration of the liver of (CBA X C57BL)F1 mice and the degree of its mononuclear infiltration was studied. Resection of the 2/3 of the liver mass was performed 1 and 5 days and 2 months after zymosan-induced mononuclear infiltration. The synthesis of DNA and mitotic activity of hepatocytes in the liver with infiltrations was higher as compared with control. The rate of liver regeneration was dependent on the scope of the mononuclear infiltration, reaching a maximum provided liver resection was made 5 days after injection of zymosan granules.

[Dependence of mononuclear infiltration of the liver on hepatocyte proliferation]. / Zavisimost' mononuklearnoi infil'tratsii pecheni ot proliferatsii gepatotsitov.

Partial liver resection (two-thirds) performed in (CBA X C57BL)F1 mice 2-4 or 24 h after intravenous injection of 2 mg zymozan led to retardation of the formation of mononuclear infiltrates in the liver and the lung. In control sham-operated animals, the first signs of infiltration appeared on the 2nd, whereas in mice with partial liver resection ( PLR ) on the 5th day after zymozan -induced stimulation of liver macrophages. If mice underwent PLR 5 days after zymozan injection, the preformed mononuclear infiltrates experienced the reverse development. PLR did not abolish monocytosis which was observed after zymozan injection. On the other hand, when mice received hydrocortisone in a dose of 125 mg/kg, the zymozan -induced infiltration in the liver as well as monocytosis were blocked. It is assumed that depression of mononuclear infiltration in the liver and the lung after liver resection is linked with a specific effect of proliferating hepatocytes rather than with the stress-induced mobilization of glucocorticoids.