[Zinc in the blood serum and tissues in patients with planoepithelial carcinoma of the larynx]. / Cynk w surowicy krwi i tkankach u chorych na raka plaskonablonkowego krtani.

Serum and tissue zinc concentrations in 30 subjects with operable squamous cell carcinoma of the larynx, aged 36-56 were determined by atomic absorption spectrophotometry. The concentration of this cation in cancerous tissues and in unchanged homologous tissues do not differ significantly. Mean zinc serum level was lower before treatment.

[Urinary magnesium levels in precancerous conditions and various stages of squamous cell carcinoma of the larynx]. / Magnez w moczu w stanach przedrakowych oraz róznych stadiach raka plaskonablonkowego krtani.

In 100 cases with different stages of planoepithelial laryngeal cancer and in 13 precancerous changes the urine magnesium levels were examined two times by means of absorptive spectrometry before surgery and half a year after. In precancerous period group (I stage according to WHO) no differences were found in comparison to the control group. As the disease progressed the urine magnesium level deteriorated according to the cancer stages. In IV stage the level was the lowest (P less than 0.01). The normalization of the urine magnesium level was found in some cases 6 months after surgery and radiotherapy.

[Magnesium content of laryngeal precancerous conditions and laryngeal cancers]. / Der Magnesiumgehalt bei Larynxpräkanzerosen und Larynxkarzinomen.

The content of magnesium in tissues, erythrocytes and serum was analysed by atomic absorption spectrometry. A higher concentration of magnesium was found in malignant laryngeal tissue and in lymph nodes of the neck compared to homologous pre-cancerous tissue. In pre-cancerous lesions of the larynx the magnesium concentration of the erythrocytes and serum lay at the lower limit of normal. In patients with cancer of the larynx, the magnesium concentration was considerably below the normal levels and continued to decline as the disease progressed.

Red blood cell, serum and tissue magnesium levels in subjects with laryngeal carcinoma.

Red blood cell, serum and tissue Mg concentrations in 100 subjects with aged 34-78, with squamous cell carcinoma of the larynx were determined by atomic absorption spectrophotometry. The concentration of this cation in cancerous tissues was found to be about twice as high as in the unchanged homologous tissues of the host. This was accompanied by a systemic deficiency manifesting itself by a decreased Mg concentration in red blood cells, serum and muscles which became more pronounced as the disease advanced, and returned to normal after radical treatment.