ABSTRACT
The sampling included 23 children with glycogen disease. All patients were examined using system of continuous monitoring of content of glucose applied during 72 hours. It was established that hypoglycemia was detected in 19 (82.6%) children. At that, in 7 (30.4%) children the level of glucose was below detected range (< 2.2 mmol/l). In patients ignoring proposed recommendations (lack of compliance) expression of hypoglycemia was reliably higher than in children being on a diet and following recommendations of physician. In primary patients as compared with secondary patients rate and duration of hypoglycemia in blood serum activity of aspartate aminotransferase also was reliably higher. Independently of all that, the more frequently hypoglycemia developed the more expressed hypoglycemia was. Therefore, continuous monitoring of content of glucose in intercellular fluid is an effective instrument for detecting degree of compensation of carbohydrate metabolism in patients with glycogen disease. The day continuous monitoring of level of glucose permits to provide the most complete picture of fluctuations of glycaemia during a day. The obtained data can be used as a basis for composing an optimal algorithm of diet therapy.
