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1.
J Geophys Res Atmos ; 126(21): e2021JD035087, 2021 Nov 16.
Article in English | MEDLINE | ID: mdl-35865264

ABSTRACT

This study investigates how wind shear and momentum fluxes in the surface- and boundary layer vary across wind and cloud regimes. We use a 9-year-long data set from the Cabauw observatory complemented by (8.2 × 8.2 k m 2 ) daily Large Eddy Simulation (LES) hindcasts. An automated algorithm classifies observed and simulated days into different cloud regimes: (a) clear-sky days, (b) days with shallow convective clouds rooted in the surface layer, with two ranges of cloud cover, and (c) non-convective cloud days. Categorized days in observations and LES do not always match, particularly the number of non-convective cloud days are underestimated in the LES, which likes to develop convection. However, the climatology and diurnal cycle of winds for each regime are very similar in LES and observations, strengthening our confidence in LES' skill to reproduce certain clouds for certain atmospheric states. Along-wind momentum flux profiles are similar across all regimes, but large cloud cover (convective and non-convective) days have larger total momentum flux distributed over a deeper layer, with up to 30% of the surface flux still present near cloud base. The clear-sky and especially shallow cumulus regime with low cloud cover have notably larger crosswind momentum fluxes in the boundary layer. Surface-layer wind shear at daytime is smallest in the shallow cumulus regimes, having deeper boundary layers and a steady increase in surface layer wind speed during daytime. Compared to clear-sky days at a similar stability, convective cloud regimes have smaller surface-layer wind shear and larger surface friction than estimated by Monin-Obukhov Similarity Theory.

2.
Hum Reprod ; 27(2): 457-67, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22144420

ABSTRACT

BACKGROUND: Based on a presumed negative impact of overweight and obesity on reproductive capacity and pregnancy outcome, some national guidelines and clinicians have argued that there should be an upper limit for a woman's BMI to access assisted reproductive technologies (ART). However, evidence on the risk of complications or expected success rate of ART in obese women is scarce. We therefore performed a systematic review on the subject. METHODS: We searched the literature for studies reporting on complications or success rates in overweight and obese women undergoing ART. Articles were scored on methodological quality. We calculated pooled odds ratios (ORs) to express the association between overweight and obesity on the one hand, and complications and success rates of ART on the other hand. We only pooled results if data were available per woman instead of per cycle or embryo transfer. RESULTS: We detected 14 studies that reported on the association between overweight and complications during or after ART, of which 6 reported on ovarian hyperstimulation syndrome (OHSS), 7 on multiple pregnancies and 6 on ectopic pregnancies. None of the individual studies found a positive association between overweight and ART complications. The pooled ORs for overweight versus normal weight for OHSS, multiple pregnancy and ectopic pregnancy were 1.0 [95% confidence interval (CI) 0.77-1.3], 0.97 (95% CI 0.91-1.04) and 0.96 (95% CI 0.54-1.7), respectively. In 27 studies that reported on BMI and the success of ART, the pooled ORs for overweight versus normal weight on live birth, ongoing and clinical pregnancy following ART were OR 0.90 (95% CI 0.82-1.0), 1.01 (95% CI 0.75-1.4) and OR 0.94 (95% CI 0.69-1.3), respectively. CONCLUSIONS: Data on complications following ART are scarce and therefore a registration system should be implemented in order to gain more insight into this subject. In the available literature, there is no evidence of overweight or obesity increasing the risk of complications following ART. Furthermore, they only marginally reduce the success rates. Based on the currently available data, overweight and obesity in itself should not be a reason to withhold ART.


Subject(s)
Infertility, Female/therapy , Obesity/complications , Overweight/complications , Pregnancy Rate , Reproductive Techniques, Assisted/adverse effects , Adult , Body Mass Index , Evidence-Based Medicine , Female , Humans , Infertility, Female/complications , Ovarian Hyperstimulation Syndrome/etiology , Pregnancy , Pregnancy, Ectopic/etiology , Pregnancy, Multiple
3.
Hum Reprod Update ; 16(3): 246-54, 2010.
Article in English | MEDLINE | ID: mdl-20056674

ABSTRACT

BACKGROUND: Overweight and obesity are an epidemic in Western society, and have a strong impact on fertility. We studied the consequences of overweight and obesity with respect to fecundity, costs of fertility treatment and pregnancy outcome in subfertile women. METHODS: We searched the literature for systematic reviews and large studies reporting on the effect of weight on both fecundity and pregnancy outcome in subfertile women. We collected data on costs of treatment with ovulation induction, intrauterine insemination and in vitro fertilization, as well as costs of pregnancy complications. We calculated, for ovulatory and anovulatory women separately, the number of expected pregnancies, complications and costs in a hypothetical cohort of 1000 normal weight, overweight and obese women each. RESULTS: In our hypothetical cohort of 1000 women, compared with women with normal weight, live birth was decreased by 14 and 15% (from 806 live births to 692 and 687 live births) in overweight and obese anovulatory women, respectively, for ovulatory women it was decreased by 22 and 24% (from 698 live births to 546 and 531 live births), respectively. These outcomes were associated with an increase in the number of complications and associated costs leading to cost per live birth in anovulatory overweight and obese women were 54 and 100% higher than their normal weight counterparts, for ovulatory women they were 44 and 70% higher, respectively. CONCLUSIONS: Overweight and obese subfertile women have a reduced probability of successful fertility treatment and their pregnancies are associated with more complications and higher costs.


Subject(s)
Infertility, Female/complications , Infertility, Female/therapy , Obesity/economics , Overweight/economics , Reproductive Techniques, Assisted/economics , Anovulation , Body Mass Index , Cost of Illness , Female , Fertility , Fertilization in Vitro/economics , Humans , Insemination, Artificial/economics , Insemination, Artificial/methods , Models, Economic , Obesity/complications , Overweight/complications , Ovulation Induction/economics , Pregnancy , Pregnancy Complications/economics , Pregnancy Outcome
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