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Adm Policy Ment Health ; 47(2): 291-299, 2020 03.
Article in English | MEDLINE | ID: mdl-31620909

ABSTRACT

Use of methylphenidate in children has increased substantially, despite conflicting evidence regarding efficacy. In this study, prescription data were analyzed in relation to the publication of new evidence regarding efficacy. Incidence rates and prescribed doses of methylphenidate increased, with a decline during the last few years. Duration of use is still increasing. In half of the cases, starting dosages are higher than recommended in guidelines. There was little evidence that publication of new evidence directly influenced the use of methylphenidate. Recent and critical study findings should receive more attention to contribute to the development and use of treatment guidelines for ADHD and evidence-based methylphenidate use.


Subject(s)
Attention Deficit Disorder with Hyperactivity/drug therapy , Central Nervous System Stimulants/administration & dosage , Drug Utilization/statistics & numerical data , Methylphenidate/administration & dosage , Prescriptions/statistics & numerical data , Adolescent , Attention Deficit Disorder with Hyperactivity/epidemiology , Central Nervous System Stimulants/therapeutic use , Child , Child, Preschool , Dose-Response Relationship, Drug , Female , Humans , Male , Methylphenidate/therapeutic use , Netherlands/epidemiology , Practice Guidelines as Topic , Practice Patterns, Physicians'/statistics & numerical data
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