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1.
J Cardiol ; 17(4): 671-82, 1987 Dec.
Article in Japanese | MEDLINE | ID: mdl-3506597

ABSTRACT

To evaluate how the intraventricular blood flow is affected by the size of a left ventricular aneurysm and ventricular dysfunction, systolic left ventricular blood flow patterns were evaluated using two-dimensional Doppler flow images (real-time 2-D Doppler echo). The subjects consisted of 10 normal controls, 35 patients with anteroseptal infarction, two patients with inferior infarction and five patients with anteroseptal-inferior infarctions. The systolic period was divided into three subsets; early, mid- and end-systole. Forty-two patients with myocardial infarction were classified into three groups according to the left ventricular inflow patterns on real-time 2-D Doppler echo using the apical left ventricular long-axis approach; i.e., inflow signals confined to early systole (Group I), visualized up to mid-systole (Group II) and end-systole (Group III). Left ventricular end-diastolic dimension (LVDd), left ventricular end-systolic dimension (LVDs), and % non-contractile circumference (delta L) were calculated by the same echocardiographic approach. Ejection fraction (EF) was calculated by left ventricular cineangiography using the Simpson's method. The left ventricular inflow Doppler signals in the normal controls and Group I turned in the apex and then directed toward the left ventricular outflow tract during late diastole and early systole. Significant differences in EF were observed among the three groups. EF in Group I, II and III was 53 +/- 9%, 41 +/- 8% and 29 +/- 7%, respectively. However, LVDd, LVDs and delta L had the largest values in Group III and the smallest values in Group I. LVDd, LVDs and delta L were smallest in Group I and largest in Group III. In the normal controls, the left ventricular inflow signals proceeded to the apex and directed toward the left ventricular outflow tract in the early systolic period. Various changes in the inflow pattern were observed in patients with myocardial infarction and severe wall motion abnormalities, including delayed timing in proceeding from the apex to the left ventricular outflow tract, stagnant blood at the apex and further inflow of blood toward the apex even during end-systole. The patients with sustained inflow during late systole had hypofunction of the left ventricle as demonstrated by smaller EF and larger LVDd, LVDs, and delta L. In conclusion, the observation of intracardiac blood flows by real-time 2-D Doppler echo is of help in evaluating the severity of myocardial infarction.


Subject(s)
Echocardiography, Doppler , Heart Aneurysm/physiopathology , Myocardial Infarction/physiopathology , Adult , Aged , Blood Flow Velocity , Female , Heart Aneurysm/complications , Heart Ventricles/physiopathology , Humans , Male , Middle Aged , Myocardial Infarction/complications , Systole
2.
J Cardiol ; 17(4): 699-710, 1987 Dec.
Article in Japanese | MEDLINE | ID: mdl-3509831

ABSTRACT

The reliability of measuring the myocardial infarct zone by two-dimensional echocardiography (2 DE) was compared with that by regional myocardial blood flow as evaluated by single photon emission computed tomography (SPECT) in 47 patients with old myocardial infarction, with ventricular aneurysm (An group; n = 15), and without ventricular aneurysm (Non-An group; n = 32). Short-axis images of the left ventricle at the level of the mitral valve, the papillary muscles, and the apex were obtained both by 2DE and SPECT. The left ventricular wall was divided into 36 segments in 2DE and 40 segments in SPECT with reference points at the posterior end of the right side of the interventricular septum. The segments in which the radial shortening on 2DE and the 201Tl uptake index on SPECT were below one standard deviation from the means of 10 normal subjects were defined as those with abnormal wall motion and hypoperfused areas, respectively. The relationships between these findings were studied. The extent of apical movement was measured by left ventricular cineangiography in each case, and was compared between the An and Non-An groups. 1. Wall motion abnormalities on 2DE and hypoperfusion on SPECT showed a correspondence of 81% in the An group and 78% in the Non-An group at the level of the mitral valve, and 78% in the An group and 76% in the Non-An group at the papillary muscle level. However, a better correspondence was observed in the An group (84%) as compared to the Non-An group (64%) at the level of the apex. 2. Apical movement assessed by cineangiography showed more extensive changes in the Non-An group than in the An group (2.3 +/- 0.9 mm vs 4.1 +/- 1.7 mm in the RAO view, 2.4 +/- 1.9 mm vs 5.3 +/- 2.1 mm in the LAO view). From these observations, it was suspected that the cause of disparity between radial shortening and the 201Tl uptake index at the level of the apex is related to the cardiac movement of the apex toward the base during systole. 3. Since wall motion abnormalities demonstrated by radial shortening (2DE) and hypoperfusion indicated by the 201Tl uptake index (SPECT) generally corresponded well, 2DE was thought to be a useful method for evaluating myocardial infarct zone.


Subject(s)
Echocardiography, Doppler , Myocardial Infarction/diagnosis , Thallium Radioisotopes , Tomography, Emission-Computed , Aged , Coronary Circulation , Heart Aneurysm/complications , Humans , Middle Aged , Myocardial Infarction/complications , Myocardial Infarction/physiopathology
3.
J Cardiogr ; 15(1): 181-95, 1985 Mar.
Article in Japanese | MEDLINE | ID: mdl-2933475

ABSTRACT

Cross-sectional echocardiography facilitates recognizing dissecting aortic aneurysms, but the diagnosis of abnormalities of the descending aorta in the retrocardiac portion is difficult. We prospectively designed to assess the usefulness of a new echocardiographic technique in defining the retrocardiac descending thoracic aorta in its long and short axes. Two patients with dissecting aneurysms involving the retrocardiac descending aorta were studied in the 90 degrees right lateral position using a Toshiba SSH-11A or SSH-40A cross-sectional echocardiographic apparatus. The transducer was positioned in the third or fourth intercostal space closely to the left of the thoracic vertebrae, and the ultrasonic beam was directed toward the retrocardiac descending aorta from the patient's back. The descending thoracic aorta was identified in its long axis as a straight tubular structure with parallel walls. The transducer was then rotated approximately 90 degrees, to visualize the descending aorta in its short axis as a circular structure. This "paravertebral approach" has not previously been reported. In both patients, the retrocardiac descending thoracic aorta was clearly visualized in its long and short axes, and the oscillating intimal flap was visualized within the descending aorta in the paravertebral approach. Pulsed Doppler echocardiography (PDE) using the long-axis paravertebral approach identified the flow in the false and true lumens of the descending thoracic aorta. Flow patterns including the peak flow velocity and the velocity profile obviously varied between the true and false lumens. The peak flow velocities in the former were extremely high compared to those in the latter. The former exhibited laminar profiles, but the latter showed some spectral broadening. By the same approach, the entrance tear was explored and the jet flow through the tear was detected in Case 1 by PDE, which had high flow velocity with wide spectral broadening and aliasing in systole and also had relatively low flow velocity with some spectral broadening in diastole. To our knowledge, there has been no previous report of detecting flow at the entrance tear by PDE. These cross-sectional echocardiographic studies suggest that the paravertebral approach may prove helpful in initially evaluating patients with symptoms or signs suggestive of acute dissecting aneurysms. However, comprehensive studies are necessary to define the sensitivity and specificity of these echocardiographic techniques in recognizing all types of dissecting aneurysms.


Subject(s)
Aortic Aneurysm/diagnosis , Aortic Dissection/diagnosis , Echocardiography/methods , Aged , Cardiomegaly/diagnosis , Electrocardiography , Humans , Male , Middle Aged , Spine , Transducers
4.
J Cardiogr ; 15(1): 67-78, 1985 Mar.
Article in Japanese | MEDLINE | ID: mdl-3934295

ABSTRACT

Intracardiac and arterial thrombi were examined by scintigraphy using In-111-oxine labeled autologous platelets. In 22 cases of myocardial infarction including six with ventricular aneurysms, four had positive findings of thrombi on imaging and detected also by echocardiography. All four had ventricular aneurysms. The so-called "moya-moya" echoes (fuzzy echoes) were demonstrated in two of these four cases. We encountered two cases with positive findings on imaging in 13 with mitral valve disease. These two had systemic embolic episodes after scintigraphic examination. "Moya-moya" echoes were detected in the left atrial cavity in four with negative findings on imaging. Positive images were obtained in two of three with acute arterial occlusive disease, and in both cases platelet deposition was observed in the proximal site of obstruction. Though thrombectomy was performed for one of these two cases, no thrombus was detected at the site of platelet deposition. After one month, re-examination revealed only negative findings in all sites in both these patients. In the six cases of aortic aneurysm, three had platelet deposition within their aneurysms, and surgery was performed for these positive cases, but one of them had no thrombus. Positive images were obtained in only one of seven patients with chronic arterial occlusive disease. Coagulation tests and platelet studies were investigated for patients with positive or negative platelet scans. Only the data of the thrombo-test showed a significant difference (97 +/- 9% vs 23 +/- 7%, p less than 0.001). Three cases of positive imaging became negative after anticoagulant therapy. We tried ECT for eight cases 24 hours after injection of In-111-oxine labeled platelets. Three cases showed clear images of thrombi, while the planar images could not detect them at an early stage. Therefore, we propose that ECT can be a useful technique for diagnosing intracardiac thrombi in early stage.


Subject(s)
Blood Platelets , Heart Diseases/diagnostic imaging , Hydroxyquinolines , Indium , Organometallic Compounds , Oxyquinoline , Thrombosis/diagnostic imaging , Aged , Arterial Occlusive Diseases/diagnostic imaging , Child , Child, Preschool , Humans , Infant , Infant, Newborn , Male , Myocardial Infarction/diagnostic imaging , Oxyquinoline/analogs & derivatives , Tomography, Emission-Computed
5.
J Cardiogr ; 14(2): 267-79, 1984 Aug.
Article in Japanese | MEDLINE | ID: mdl-6533191

ABSTRACT

So-called "moyamoya" echoes identified by two-dimensional echocardiography (2 DE) in two cases with ventricular aneurysm were studied by pulsed Doppler echocardiography. The results were as follows: The flow velocity patterns in the left ventricle obtained by pulsed Doppler method were consistent with those observed by the real time 2DE method; the moyamoya echoes moved in a slow, circular fashion, and only a flow with slow velocity toward the transducer was recorded in the posterior area, whereas only a flow with slow velocity away from the transducer was recorded along the interventricular septum during cardiac cycle. The ejection flow velocity at the left ventricular outflow tract was markedly diminished. The flow velocity of the moyamoya echoes was extremely decreased and ranged between 50 and 135 mm/sec. The velocity measurements by M-mode and pulsed Doppler echocardiography gave almost the same values. Thus, the results of the present report suggest that the moyamoya echoes behave like moving blood cells, and that the source of these echoes is the sludging in the stasis of blood.


Subject(s)
Echocardiography , Heart Aneurysm/diagnosis , Aged , Blood Flow Velocity , Coronary Disease/complications , Coronary Disease/diagnosis , Coronary Disease/physiopathology , Female , Heart Aneurysm/complications , Heart Aneurysm/physiopathology , Humans , Male , Middle Aged
6.
J Cardiogr ; 14(2): 403-14, 1984 Aug.
Article in Japanese | MEDLINE | ID: mdl-6533200

ABSTRACT

Echocardiographic analysis of right ventricular ejection time (RVET), pre-ejection time (RVPEP), RVPEP/ET and isovolumic relaxation time (RVIRT) was performed in patients with acute or chronic right ventricular pressure overloading. Fifty-five patients undergoing right ventricular cardiac catheterization, were categorized into seven groups; 11 patients with atrial septal defect (ASD) without pulmonary hypertension (PH) (group 1), 12 with ASD with PH (group 2), six with mitral stenosis (MS) without PH (group 3), nine with MS with PH (group 4), seven with primary pulmonary hypertension (PPH) (group 5), seven with acute pulmonary embolism (PE) (group 6), and three patients with convalescence of PE (group 7). Corrected RVIRT (RVIRTc) and RVET (RVETc) were calculated by regression analysis correlating with heart rate in normal subjects. RVIRTc, RVETc, RVPEP and RVPEP/ET in seven groups were significantly correlated with systolic pulmonary artery pressure (SPAP) (r = 0.62, p less than 0.001; r = -0.41, p less than 0.01; r = 0.61, p less than 0.001; r = 0.65, p less than 0.001, respectively), but RVDd did not correlate with SPAP (r = 0.370, p less than 0.05). Comparing acute right ventricular pressure overloading group (group 6) with each of chronic right ventricular pressure overloading groups (groups 2, 4, 5, and 7), RVIRTc and RVDd were significantly increased in the former than the latter, but RVETc, RVPEP and RVPEP/ET were not significantly different in both groups. There was a significant correlation between RVIRTc and RVPEP/ET in chronic pressure overloading, but not in acute pressure overloading. We concluded that early diastolic RV relaxation and systolic performance were both impaired by increased afterload in chronic pressure overloading. In acute pressure overloading, however, early diastolic RV relaxation was more significantly impaired possibly because of acute changes of muscle architectures due to acute right ventricular expansion and anoxia.


Subject(s)
Cardiac Output , Echocardiography , Heart Diseases/physiopathology , Stroke Volume , Blood Pressure , Electrocardiography , Heart Septal Defects, Atrial/physiopathology , Humans , Hypertension, Pulmonary/physiopathology , Mitral Valve Stenosis/physiopathology , Phonocardiography , Pulmonary Embolism/physiopathology
7.
J Cardiogr ; 13(3): 633-48, 1983 Sep.
Article in Japanese | MEDLINE | ID: mdl-6086775

ABSTRACT

Five cases of miscellaneous right atrial mass were described to illustrate the very valuable diagnostic contribution of two-dimensional echocardiography (2DE). Two patients had a large myxoma in the right atrium, and other two had an extension of hepatoma into the right atrium through the inferior vena cava. The fifth patient with a past history of myocardial infarction had a floating right atrial thrombus. The myxoma in the right atrium appeared as a mottled, ovoid, and sharply demarcated mobile mass attached to the interatrial septum. The diagnosis of these two patients was confirmed at operation. The right atrial myxoma in the first case weighed 310 g and filled almost the entire right atrium and right ventricle. To our knowledge, this was the largest myxoma among previously reported cases. The hepatoma extended into the right atrium resembled myxoma, but was obscurely demarcated. The 2DE was useful to localize a large immobile mass extending into the right atrium. All these right atrial tumors were adequately demonstrated in the right lateral decubitus position with the transducer over the right parasternal position. In the fifth case, bedside real-time 2DE was performed after the attack of pulmonary thromboembolism, and an irregular echogenic mass was seen to float freely, suggesting a thrombus. Following the immediate anticoagulant therapy with heparin, the thrombus echo was no longer visible by 2DE. It was concluded that 2DE should be extensively applied to diagnose right atrial tumors or thrombi.


Subject(s)
Echocardiography/methods , Heart Diseases/diagnosis , Heart Neoplasms/diagnosis , Myxoma/diagnosis , Thrombosis/diagnosis , Adult , Aged , Carcinoma, Hepatocellular/diagnosis , Carcinoma, Hepatocellular/pathology , Female , Heart Atria , Humans , Liver Neoplasms/diagnosis , Liver Neoplasms/pathology , Male , Middle Aged , Myocardial Infarction/complications , Neoplasm Invasiveness
8.
J Cardiogr ; 12(4): 825-38, 1982 Dec.
Article in Japanese | MEDLINE | ID: mdl-7186004

ABSTRACT

The echocardiographic and clinical study was performed in six patients (three acute pulmonary embolism, one for each hypertensive cardiomyopathy, ischemic heart disease and primary pulmonary hypertension) who had a diastolic monophasic triangular pattern of the tricuspid valve echogram. Left-sided and right-sided IRT / square root R-R, ICT / square root R-R, PEP, Q-Mc and Q-Tc, and PEP / ET (IRT; isovolumic relaxation time, ICT; isovolumic contraction time, PEP; preejection time, Q-Mc or Q-Tc; interval of the Q wave of the ECG to the closing point of the mitral or tricuspid valve, and ET; ejection time) were measured from echocardiograms, and the comparisons of these parameters were made between two kinds of echogram with or without triangular pattern of the tricuspid valve. There were no significant differences in the left-sided parameters between the two kinds of echocardiograms. The mitral valve echogram showed a persistent M-shaped pattern irrespective of the pattern of the tricuspid valve. Right-sided IRT / square root R-R and ICT / square root R-R were significantly prolonged and Q-Tc was significantly shortened in the echogram with a triangular pattern of the tricuspid valve. Right ventricular (RV) catheterization was performed using a Swan-Ganz catheter in four patients with the triangular pattern of the tricuspid valve echogram. The mean pulmonary artery pressure ranged from 24 to 96 mmHg (40 mmHg on an average) and RV end-diastolic pressure from 8 to 17 mmHg (12 mmHg on An average). The possible explanation for the production of the triangular tricuspid valve echogram was an impaired early diastolic relaxation and increased stiffness of the RV due to the acute pressure overloading, resulting in a delayed opening and an early closing of the tricuspid valve. We conclude that a diastolic monophasic triangular pattern of the tricuspid valve echogram is a reflection of an impaired early diastolic relaxation and an increased end-diastolic stiffness of the RV.


Subject(s)
Echocardiography , Tricuspid Valve/physiopathology , Adult , Aged , Coronary Disease/physiopathology , Humans , Hypertension, Pulmonary/physiopathology , Middle Aged , Pulmonary Embolism/physiopathology
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