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1.
Khirurgiia (Mosk) ; (9): 48-53, 2013.
Article in Russian | MEDLINE | ID: mdl-24077507

ABSTRACT

The experience of 127 hernioplastics for postoperative ventral hernia using different methods during the period of 2000-2010 yy was analyzed. The algorithm for incisional ventral hernia has been worked out, considering the presence of recurrence risk factors and biochemical parameters. The results of treatment of 18 patients, using the algorithm, showed no local and general postoperative complications, which allowed to consider it as the evidence of algorythm's effectiveness.


Subject(s)
Abdominal Wall/surgery , Hernia, Ventral/surgery , Herniorrhaphy , Postoperative Complications , Abdominal Wound Closure Techniques , Adult , Algorithms , Female , Hernia, Ventral/epidemiology , Hernia, Ventral/etiology , Herniorrhaphy/adverse effects , Herniorrhaphy/methods , Herniorrhaphy/statistics & numerical data , Humans , Male , Middle Aged , Postoperative Complications/diagnosis , Postoperative Complications/epidemiology , Postoperative Complications/surgery , Recurrence , Risk Factors , Treatment Outcome
2.
Izv Akad Nauk Ser Biol ; (3): 299-311, 2001.
Article in Russian | MEDLINE | ID: mdl-11433940

ABSTRACT

The anticancer activity of Trypanosoma cruzi has been confirmed by the example of seven strains. Five virulent strains induced the infection, which inhibited sarcoma-180 growth 1.5-22.0 times. The parasites featured tumortropism; i.e., the successfully developed in cancer cells and even preferred them to normal cells. This taxis-based phenomenon was particularly pronounced at cocultivation of the normal and cancer cells. Cultures of the seven (avirulent and virulent) strains can produce an anticancer agent that selectively damages human cancer cells in vitro. The long-term anticancer effect of T. cruzi or preparations from it, as well as possible its cancer preventing effect, has been demonstrated. Three problems are discussed on the basis of the obtained and recently published data: (1) the mechanism of T. cruzi anticancer effect; (2) the nature of the anticancer agent; and (3) the distribution of the considered phenomenon among trypanosomatides. The anticancer activity of T. cruzi may be due to a combination of surface cellular antigens and an inhibiting or lysing factor.


Subject(s)
Antibiotics, Antineoplastic/metabolism , Biological Factors/metabolism , Chagas Disease/parasitology , Neoplasms/pathology , Organic Chemicals , Trypanosoma cruzi/metabolism , Animals , Antibiotics, Antineoplastic/pharmacology , Antigens, Protozoan/metabolism , Antigens, Surface/metabolism , Biological Factors/pharmacology , Chagas Disease/immunology , Humans , Neoplasm Transplantation , Neoplasms/immunology , Neoplasms/parasitology , Organ Specificity , Trypanosoma cruzi/immunology , Trypanosoma cruzi/pathogenicity , Virulence
3.
Wiad Parazytol ; 34(1): 77-8, 1988.
Article in English | MEDLINE | ID: mdl-2968721
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