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Stomatologiia (Mosk) ; 68(3): 21-3, 1989.
Article in Russian | MEDLINE | ID: mdl-2772930

ABSTRACT

Sensitivity of microflora sampled from the dental root channels of periodontitis patients to chlorhexidine, dioxidine, quinosol, Metrodgile was investigated. Chlorhexidine and dioxidine were shown to act predominantly on gram-positive and gram-negative bacteria, Metrodgile most active against anaerobic flora. High antibacterial activity of quinosol and chlorhexidine was combined with their pronounced cytotoxic effects. Metrodgile could be successfully used for preventing purulent odontogenic inflammations caused by anaerobic flora.


Subject(s)
Anti-Infective Agents, Local/therapeutic use , Periapical Granuloma/drug therapy , Anti-Infective Agents, Local/pharmacology , Anti-Infective Agents, Local/toxicity , Bacteria/drug effects , Bacteria/isolation & purification , Cells, Cultured , Chlorhexidine/pharmacology , Chlorhexidine/therapeutic use , Chlorhexidine/toxicity , Humans , Microbial Sensitivity Tests , Periapical Granuloma/microbiology , Quinoxalines/pharmacology , Quinoxalines/therapeutic use , Quinoxalines/toxicity , Solutions , Tumor Cells, Cultured
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