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1.
Tsitologiia ; 34(6): 67-73, 1992.
Article in Russian | MEDLINE | ID: mdl-1455560

ABSTRACT

Flow cytometry analysis of the DNA content of human decidual cells at the physiologically normal pregnancy and in the case of toxicosis was carried out. During the normal pregnancy DNA-histogram parameters were seen to vary: the number of S-phase cells decreased, the coefficient of variation of the G1/0 peak increased. These alterations correlated positively with the increase in the share of decidual cells with properties of terminally differentiated cells. The most pronounced quantitative alterations in variability of DNA content in G1/0 cells were observed in cases of toxicosis of pregnancy. Phenomena of variability of the nuclear DNA in the terminally differentiated decidual cells is considered to be a sign of cell death through apoptosis.


Subject(s)
DNA/biosynthesis , Decidua/metabolism , Adolescent , Adult , Cell Differentiation/physiology , Cellular Senescence/physiology , DNA/analysis , Decidua/chemistry , Decidua/cytology , Female , Flow Cytometry , Humans , Pre-Eclampsia/metabolism , Pre-Eclampsia/pathology , Pregnancy
2.
Akush Ginekol (Mosk) ; (3): 18-22, 1991 Mar.
Article in Russian | MEDLINE | ID: mdl-2058768

ABSTRACT

The paper provides the results of a 8-year practice of the Leningrad City Obstetric and Hematological Center. The setting up of the center has ensured effective prevention of labour bleedings in the following pathological conditions of pregnants: gestosis, varicosity, anemic syndrome, and blood diseases. An algorithm has been developed for examining pregnants; recommendations are given for the management of pregnancy, labour and for the correction of hemostasiological disorders.


Subject(s)
Hemostasis/physiology , Pregnancy Complications, Hematologic/prevention & control , Uterine Hemorrhage/prevention & control , Anemia, Hypochromic/blood , Anemia, Hypochromic/complications , Anemia, Hypochromic/therapy , Blood Coagulation/physiology , Female , Humans , Pre-Eclampsia/blood , Pre-Eclampsia/complications , Pre-Eclampsia/therapy , Pregnancy , Pregnancy Complications, Hematologic/blood , Uterine Hemorrhage/blood , Uterine Hemorrhage/etiology , Uterus/blood supply , Varicose Veins/blood , Varicose Veins/complications , Varicose Veins/therapy
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