1.
Bioorg Med Chem Lett
; 9(9): 1239-42, 1999 May 03.
Article
in English
| MEDLINE
| ID: mdl-10340606
ABSTRACT
An alternative solid support for oligonucleotide synthesis was developed by coupling a polymer colloid to a modified polyethylene filter disc. The functions on the polymer colloid not used for attachment to the surface were derivatized with a Jeffamine diamine and loaded with appropriate deoxynucleoside succinates. The performance of this support system was evaluated and compared to existing resins.