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Diabetes Res Clin Pract ; 83(2): e40-2, 2009 Feb.
Article in English | MEDLINE | ID: mdl-19108925

ABSTRACT

Effects of glucomannan as a supplementary treatment in type 2 diabetes mellitus were investigated by measuring ghrelin, leptin and insulin responses to OGTT. Glucomannan enhanced prandial ghrelin reduction when given before glucose load and impeded the rise of fasting ghrelin after 4-week supplement. Ghrelin-induced feeding may be attenuated by glucomannan.


Subject(s)
Diabetes Mellitus, Type 2/diet therapy , Ghrelin/blood , Leptin/blood , Mannans/pharmacology , Blood Glucose/metabolism , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/metabolism , Dietary Supplements , Fasting/blood , Fasting/metabolism , Glucose Tolerance Test , Humans , Insulin/blood , Insulin Resistance/physiology , Placebos , Postprandial Period/drug effects , Postprandial Period/physiology , Time Factors
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