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[Effect of cytostatics on tumor cells]. / O deistvii tsitostatikov na opukholevye kletki.

Sergel', O S; Kopeiko, I P; Kachkov, A P.

Sov Med ; (12): 53-6, 1980.

Article in Russian | MEDLINE | ID: mdl-6784250

Subject(s)

Breast Neoplasms/drug therapy , Cyclophosphamide/therapeutic use , Lung Neoplasms/drug therapy , Mesothelioma/drug therapy , Thiotepa/therapeutic use , Adult , Aged , Breast Neoplasms/pathology , Female , Humans , Lung Neoplasms/pathology , Male , Mesothelioma/pathology , Middle Aged , Neoplasm Recurrence, Local/drug therapy , Neoplasm Recurrence, Local/pathology

[Pulmonary artery embolism from echinococcal cysts]. / Emboliia legochnoi arterii ékhinokokkovymi puzyriami.

Vishnevskii, A A; Mazhorov, V A; Kopeiko, I P; Rubetskoi, L S; Savvina, T V.

Klin Med (Mosk) ; 57(12): 76-80, 1979 Dec.

Article in Russian | MEDLINE | ID: mdl-533987

Subject(s)

Echinococcosis/complications , Pulmonary Embolism/etiology , Adult , Echinococcosis/pathology , Heart Diseases/complications , Heart Diseases/parasitology , Heart Diseases/pathology , Humans , Male , Pulmonary Embolism/pathology

[Pharmacokinetics of rifampicin in single and repeated administration to patients with inflammatory processes in the lungs of nontuberculotic etiology]. / Farmakokinetika rifampitsina pri odnokratnom i povtornom vvedenii bol'nym s vospalitel'nymi protsessami netuberkuleznoi étiologii v legkikh

Makarenkova, R V; Kopeiko, I P.

Antibiotiki ; 22(3): 259-60, 1977 Mar.

Article in Russian | MEDLINE | ID: mdl-848920

ABSTRACT

Rifampicin is a broad spectrum semisynthetic antibiotic of the group of rifampicins. It is active against both grampositive and gramnegative organisms and mycobacteria. The studies on the pharmacokinetics of rifampicin showed that the drug was well absorbed from the gastro-intestinal tract. After a single administration of rifampicin in a dose of 150 mg its maximum concentration in the blood was registered in an hour. This concentration was preserved at the therapeutic level for 5 hours. Practically no accumulation of rifampicin was observed in its use in a dose of 150 mg 4 times a day for 5 days. Perspectivity of rifampicin use in the treatment of patients with inflammatory processes in the lungs of non-tuberculosis etiology was shown.

Subject(s)

Lung Diseases/drug therapy , Rifampin/administration & dosage , Administration, Oral , Adult , Biopharmaceutics , Humans , Intestinal Absorption/drug effects , Kinetics , Middle Aged , Time Factors

[Absorption and excretion of ampicillin and carbenicillin in surgical cases]. / Vsasyvanie i vyvedenie ampitsillina i karbenitsillina u khirurgicheskikh bol'nykh.

Iakovlev, V P; Bulgakov, G A; Kopeiko, I P; Lurie, L A.

Antibiotiki ; 18(5): 470-3, 1973 May.

Article in Russian | MEDLINE | ID: mdl-4781220

Subject(s)

Ampicillin/metabolism , Carbenicillin/metabolism , Administration, Oral , Ampicillin/administration & dosage , Ampicillin/urine , Carbenicillin/administration & dosage , Carbenicillin/urine , Humans , Injections, Intramuscular , Postoperative Complications/urine

[Study of ampicillin distribution in cases with purulent and tumor diseases of the lungs]. / Izuchenie raspredeleniia ampitsillina u bol'nykh a nagnoitel'nymi i opukholevymi zabolevaniiami legkikh.

Iakovlev, V P; Kopeiko, I P; Golovteev, V V.

Antibiotiki ; 17(2): 163-5, 1972 Feb.

Article in Russian | MEDLINE | ID: mdl-5023461

Subject(s)

Ampicillin/metabolism , Lung Diseases/metabolism , Lung Neoplasms/metabolism , Adult , Aged , Bronchiectasis/metabolism , Female , Humans , Lung Abscess/metabolism , Male , Middle Aged , Suppuration/metabolism

[Circulation of isoxazolyl penicillins in surgical patients]. / Tsirkuliatsiia izoksazolilpenitsillinov u khirurgicheskikh bol'nykh.

Iakovlev, V P; Kopeiko, I P; Govorovich, E A; Marshak, A M; Nikishina, O P.

Antibiotiki ; 16(10): 944-8, 1971 Oct.

Article in Russian | MEDLINE | ID: mdl-5138889

Subject(s)

Cloxacillin/metabolism , Oxacillin/metabolism , Penicillins/metabolism , Administration, Oral , Cloxacillin/blood , Cloxacillin/urine , Dicloxacillin/blood , Dicloxacillin/metabolism , Dicloxacillin/urine , Endocarditis, Bacterial/drug therapy , Humans , Injections, Intramuscular , Neoplasms/blood , Neoplasms/urine , Oxacillin/administration & dosage , Oxacillin/blood , Oxacillin/urine , Penicillins/administration & dosage , Penicillins/blood , Penicillins/urine , Time Factors

[Antibiotics in complex treatment of chronic suppurative lung diseases]. / Primenenie antibiotikov v komplekse lecheniia khronicheskikh nagnoitel'nykh zabolevanii legkikh.

Voropaev, M M; Govorovich, E A; Marshak, A M; Kopeiko, I P; Iakovlev, V P.

Grudn Khir ; 13(5): 46-50, 1971.

Article in Russian | MEDLINE | ID: mdl-5142796

Subject(s)

Anti-Bacterial Agents/therapeutic use , Empyema/drug therapy , Lung Diseases/drug therapy , Acute Disease , Adolescent , Adult , Chronic Disease , Female , Humans , Male , Middle Aged , Remission, Spontaneous

[Intratracheal use of morphocycline]. / Intratrakheal'noe primenenie morfotsiklina.

Lunacharskaia, T V; Kopeiko, I P.

Antibiotiki ; 13(12): 1123-6, 1968 Dec.

Article in Russian | MEDLINE | ID: mdl-4976189

Subject(s)

Anti-Bacterial Agents/pharmacology , Bacteria/drug effects , Bronchiectasis/drug therapy , Lung Abscess/drug therapy , Penicillin Resistance , Tetracycline/therapeutic use , Adolescent , Adult , Bacteria/isolation & purification , Bronchiectasis/microbiology , Chloramphenicol/pharmacology , Escherichia coli/drug effects , Female , Humans , Lung/analysis , Lung Abscess/microbiology , Male , Middle Aged , Nitrofurans/pharmacology , Penicillins/pharmacology , Proteus/drug effects , Pseudomonas aeruginosa/drug effects , Staphylococcus/drug effects , Streptococcus/drug effects , Streptomycin/pharmacology , Tetracycline/administration & dosage , Tetracycline/analysis , Tetracycline/blood , Tetracycline/pharmacology , Tetracycline/urine

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