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Adv Gerontol ; 32(4): 530-535, 2019.
Article in Russian | MEDLINE | ID: mdl-31800180

ABSTRACT

Due to the increase in the proportion of elderly women, the prevalence of ovarian cancer is increasing, which requires the search for new methods of its diagnosis. The aim of the work is to analyze the content and informativeness of immunoglobulins and phagocytic activity of peripheral blood to improve the diagnosis of ovarian cancer among elderly women. In 78 patients with ovarian cancer aged 65-70 years immunological and spectrophotometric methods studied phagocytic activity and the level of peripheral blood immunoglobulins. 42 women of the same age with no ovarian cancer served as control. The primary importance of circulating immune complexes, phagocyte migration inhibition index and neutrophil activity index for laboratory diagnosis of ovarian cancer among the elderly was established. The use of highly informative parameters of systemic immunity improves the diagnosis of ovarian cancer in the elderly.


Subject(s)
Immunoglobulins , Ovarian Neoplasms , Phagocytosis , Aged , Clinical Laboratory Techniques , Female , Humans , Immunoglobulins/blood , Neutrophils/metabolism , Ovarian Neoplasms/blood , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/physiopathology
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