ABSTRACT
Using the method of the retrograde axonal transport of horseradish peroxidase and a microelectrode technique, a population of neurons sending axons to the upper portion of the duodenum was identified in the dorsal motor nucleus of the vagus nerve. It was established that the maximal number of such neurons was located 1.0-2.5 mm rostral to the obex. The effects of their stimulation on the electrical activity of the smooth muscles of the duodenum was studied.
Subject(s)
Duodenum/innervation , Neurons/physiology , Vagus Nerve/physiology , Animals , Axons/physiology , Cats , Duodenum/anatomy & histology , Duodenum/physiology , Electric Stimulation , Electrophysiology , Evoked Potentials/physiology , Histocytochemistry , Horseradish Peroxidase , Medulla Oblongata/physiology , Stereotaxic TechniquesABSTRACT
The effects of the stimulation of various segments of the dorsal motor nucleus of the vagus on the electrical activity of the wall of the pyloric region of the stomach were studied with the use of microelectrode techniques in acute experiments in cats. It was established that the maximal changes of the parameters of the electromyogram are recorded during the stimulation of the zone of the nucleus 0(-) +1.5 mm rostral to the obex.
Subject(s)
Stomach/physiology , Vagus Nerve/physiology , Animals , Cats , Electric Stimulation , Electromyography , Electrophysiology , Evoked Potentials/physiology , Muscle Contraction/physiology , Pylorus/innervation , Pylorus/physiology , Stereotaxic Techniques , Stomach/innervationABSTRACT
In anesthetized cats, electrical stimulation of the nucleus ambiguous elicited obvious changes in electrical activity of the pylorus: slow wave frequency decreased, spike potentials either appeared or disappeared depending on stomach wall functional state. Also, the electrical stimulation decelerated the heart rate and decreased arterial blood pressure.
Subject(s)
Medulla Oblongata/physiology , Pylorus/physiology , Action Potentials/drug effects , Action Potentials/physiology , Animals , Atropine/pharmacology , Cats , Electric Stimulation/methods , Electrophysiology , Medulla Oblongata/drug effects , Microelectrodes , Muscle, Smooth/drug effects , Muscle, Smooth/physiology , Phentolamine/pharmacology , Propranolol/pharmacology , Pylorus/drug effects , Vagus Nerve/drug effects , Vagus Nerve/physiologyABSTRACT
In anesthetized cats, using method of the retrograde transport of the horseradish peroxidase and electrophysiological techniques, the dorsal motor nucleus neurons innervating upper portion of the duodenum were found. Maximal number of such neurons were found within 1.0 to 2.5 mm rostral to the obex. The effects of the neurons stimulation on the electrical activity of the duodenum smooth muscles were studied. Possible role of the dorsal motor nucleus neurons in realisation of gastro-duodenum motor reflexes is discussed.
Subject(s)
Duodenum/innervation , Neurons/cytology , Vagus Nerve/cytology , Action Potentials/physiology , Animals , Axonal Transport , Axons/physiology , Axons/ultrastructure , Cats , Duodenum/physiology , Electric Stimulation , Horseradish Peroxidase , Microelectrodes , Neurons/physiology , Vagus Nerve/physiologySubject(s)
Motor Neurons/physiology , Stomach/innervation , Vagus Nerve/physiology , Animals , Cats , Electric Stimulation , Stomach/physiologyABSTRACT
In anesthetized cats, electrical stimulation of the dorsal motor nucleus area within 0(-)+1.5 mm rostral to ohex elicited obvious changes in electrical activity of pylorus. These findings suggest the existence of topically organized parasympathetic preganglionic cell groups within the DMN--"the stomach area", which exert excitatory and inhibitory influences on the stomach smooth muscles.
