Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Euro Surveill ; 22(30)2017 07 27.
Article in English | MEDLINE | ID: mdl-28797322

ABSTRACT

We conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination and underlying conditions was collected. Using logistic regression, we measured IVE adjusted for potential confounders. We included 355 influenza A(H1N1)pdm09 cases, 110 influenza B cases, and 1,274 controls. Adjusted IVE against influenza A(H1N1)pdm09 was 42% (95% confidence interval (CI): 22 to 57). It was 59% (95% CI: 23 to 78), 48% (95% CI: 5 to 71), 43% (95% CI: 8 to 65) and 39% (95% CI: 7 to 60) in patients with diabetes mellitus, cancer, lung and heart disease, respectively. Adjusted IVE against influenza B was 52% (95% CI: 24 to 70). It was 62% (95% CI: 5 to 85), 60% (95% CI: 18 to 80) and 36% (95% CI: -23 to 67) in patients with diabetes mellitus, lung and heart disease, respectively. 2015/16 IVE estimates against hospitalised influenza in elderly people was moderate against influenza A(H1N1)pdm09 and B, including among those with diabetes mellitus, cancer, lung or heart diseases.


Subject(s)
Hospitalization/statistics & numerical data , Influenza A Virus, H1N1 Subtype/immunology , Influenza B virus/immunology , Influenza Vaccines/administration & dosage , Influenza, Human/prevention & control , Vaccine Potency , Aged , Aged, 80 and over , Europe/epidemiology , Female , Humans , Influenza A Virus, H1N1 Subtype/isolation & purification , Influenza B virus/isolation & purification , Influenza Vaccines/immunology , Influenza, Human/epidemiology , Influenza, Human/virology , Logistic Models , Male , Outcome Assessment, Health Care , Seasons , Sentinel Surveillance , Vaccination/statistics & numerical data
SELECTION OF CITATIONS
SEARCH DETAIL
...