[Functional interrelations of monoamines, thyrotropic hormone and thyroid hormones in hyperprolactinemia]. / Funktsional'nye vzaimootnosheniia monoaminov, tireotropnogo gormona i tireoidnykh gormonov pri giperprolaktinemii.

Functional interrelationships of serotonin, dopamine, prolactin, TRH and thyroid hormones in patients with hyperprolactinemia were studied. Altogether 26 patients with amenorrhea in hyperprolactinemia without clinical signs of disorder of thyroid function were examined. The levels of serotonin and dopamine were determined by spectrofluorimetry, the level of hormones was determined by a radioimmunoassay. An increase in the level of serotonin and a decrease in the level of dopamine in all the patients, a decrease in TRH and T4, and an increase in T3 were noted. The levels of monoamines, TRH and thyroid hormones showed correlation. It has been concluded that disorder of the monoaminergic mechanisms of regulation creates conditions for the rearrangement of hormonal interrelationships in the neuroendocrine functional system and determines the involvement of the hypophyseothyroid system in the pathological process. Therefore patients with hyperprolactinemia are at risk of developing thyroid functional disorders.

[Endocrinological aspects of rehabilitating women following induced abortion]. / Endokrinologicheskie aspekty reabilitatsii zhenshchin posle iskusstvennogo preryvaniia beremennosti.

PIP: A total of 107 patients were followed up after uncomplicated induced abortion performed prior to 12 weeks gestation. Daily measurements of luteinzing hormone, estrogens, and pregnanediol showed that the menstrual function and the pituitary-ovarian association were recovered within the 1st 3 cycles after the abortion by vacuum aspiration. Pituitary-ovarian disorders persisted in 10.2% of the patients. A set of rehabilitation procedures is proposed on the basis of the findings for women in need of pregnancy termination. (author's)^ieng

[Endocrine effect of L-DOPA in treating the amenorrhea-galactorrhea syndrome]. / Endokrinnyi éffekt L-DOFA pri lechenii bol'nykh s sindromom amenorei-galaktorei.

L-DOPA effect on the level of dopamine, hypophyseal luteinizing hormone and total estrogen excretion was studied in the treatment of patients with the amenorrhea-galactorrhea syndrome. The data obtained show positive L-DOPA effect on hypothalamic-hypophyseal-ovarian relationships in the majority of patients that makes it useful in therapeutic practice. The short-term course of L-DOPA administration combined with systematic studies of dopamine and hypophyseal luteinizing hormone excretion may be recommended as a functional test for differential diagnosis of central menstrual dysfunction.