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Intracellular signalling. Switching off signals.

Imboden, J B; Koretsky, G A.

Curr Biol ; 5(7): 727-9, 1995 Jul 01.

Article in English | MEDLINE | ID: mdl-7583115

ABSTRACT

In hematopoietic cells, the protein tyrosine phosphatase PTP1C appears to play a central role in the termination of signalling by receptors that activate protein tyrosine kinases.

Subject(s)

Hematopoietic Stem Cells/metabolism , Protein Tyrosine Phosphatases/metabolism , Protein-Tyrosine Kinases/metabolism , Signal Transduction , Animals , Enzyme Activation , Hematopoietic Stem Cells/enzymology , Intracellular Signaling Peptides and Proteins , Protein Tyrosine Phosphatase, Non-Receptor Type 11 , Protein Tyrosine Phosphatase, Non-Receptor Type 6

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