ABSTRACT
Overall 46 patients with allergic reactions to bee stings were examined. As a result of making skin prick, scarification and intracutaneous tests with an allergen from bee venom, allergy to bee stings was revealed in all the 46 patients, whereas only 37 patients responded to an allergen from the bee body. Specific IgE-antibodies using RAST were detected in 29 out of 31 patients. All the 29 patients had positive skin tests with an allergen from bee venom and only 22 with an allergen from the bee body. Specific histamine release was detected in all 13 patients examined by means of the indicated test. 100% coincidence was recorded with the results of intracutaneous tests with an allergen from bee venom. Only 11 out of the 13 patients had positive intracutaneous tests with an allergen from the bee body. Thus, the new Soviet allergen obtained from bee venom is effective in the diagnosis of allergy in response to bee stings.
Subject(s)
Allergens , Bee Venoms , Bees , Hypersensitivity/diagnosis , Insect Bites and Stings/diagnosis , Adolescent , Adult , Allergens/isolation & purification , Animals , Bees/immunology , Child , Drug Evaluation , Female , Humans , Male , Middle Aged , Skin TestsABSTRACT
The rheological properties of blood (viscosity, suspension stability and deformation of red blood cells) have been studied under the influence of zootoxins. It has been shown that the toxins Apis mellifera, Mesobuthus eupeus, Agkistrodon blomhoffii in vitro exert essential effect on haemorheological indexes.
Subject(s)
Blood Viscosity/drug effects , Erythrocyte Deformability/drug effects , Venoms/pharmacology , Animals , In Vitro Techniques , Melitten/pharmacology , Rats , Rheology , Scorpion Venoms/pharmacology , Snake Venoms/pharmacologySubject(s)
Amphibian Venoms/poisoning , Amphibian Venoms/analysis , Amphibian Venoms/pharmacology , Anesthetics, Local/pharmacology , Animals , Anti-Bacterial Agents/pharmacology , Antineoplastic Agents , Blood Cell Count , Capillary Permeability/drug effects , Cardiotonic Agents/pharmacology , Central Nervous System/drug effects , Cerebral Cortex/drug effects , Dogs , Female , Guinea Pigs , Heart/drug effects , Hemoglobins/analysis , Higher Nervous Activity/drug effects , Humans , Male , Mice , Neuromuscular Junction/drug effects , Radiation-Protective Agents/pharmacology , Rats , Respiration/drug effects , Shock/drug therapy , Species Specificity , Synaptic Transmission/drug effects , Vasoconstrictor Agents/pharmacologyABSTRACT
Study of neutrophil phagocytic activity in injuries to the spinal cord and spine and in damage to the spine without involvement of the spinal cord showed that injuries to the spinal cord have no specific effect on this activity. True, the phagocytic reaction is inhibited in the first 2-3 weeks after the trauma both in patients with injury to the spinal cord and spine and in those with injury only to the spine. In later periods after the trauma, however, with the neurological status remaining the same, the values of the phagocytic reaction do not differ from those in healthy persons. The level at which the spinal cord is injured hardly affects the activity of phagocytosis. The examination was conducted in 117 patients with spinal fractures 94 of whom had also sustained injury to the spinal cord.
