1.
Eur Urol Focus
; 5(5): 849-852, 2019 09.
Article
in English
| MEDLINE
| ID: mdl-29477797
ABSTRACT
The MAGNOLIA study, investigating the concept of perioperative immunotherapy in muscle- invasive bladder cancer, was prematurely terminated. The lessons learned that should be considered before initiating and conducting future clinical trials in this field are highlighted.
Subject(s)
Antigens, Neoplasm/therapeutic use , Immunotherapy , Neoplasm Proteins/therapeutic use , Urinary Bladder Neoplasms/drug therapy , Chemotherapy, Adjuvant , Clinical Trials, Phase II as Topic , Cystectomy , Double-Blind Method , Early Termination of Clinical Trials , Humans , Neoplasm Invasiveness , Randomized Controlled Trials as Topic , Recombinant Proteins/therapeutic use , Urinary Bladder Neoplasms/pathology , Urinary Bladder Neoplasms/surgery
2.
Eur Urol
; 65(3): 509-11, 2014 Mar.
Article
in English
| MEDLINE
| ID: mdl-24268503
ABSTRACT
The European Association of Urology Research Foundation has proposed that alternatives to perioperative chemotherapy should be evaluated. The MAGNOLIA study represents a unique opportunity to investigate the concept of immunotherapy in muscle-invasive bladder cancer.
Subject(s)
Urinary Bladder Neoplasms/drug therapy , Urinary Bladder Neoplasms/surgery , Chemotherapy, Adjuvant , Clinical Trials, Phase II as Topic , Humans , Neoadjuvant Therapy , Neoplasm Invasiveness , Perioperative Care , Randomized Controlled Trials as Topic , Urinary Bladder Neoplasms/pathology
3.
Eur Urol
; 62(4): 624-7, 2012 Oct.
Article
in English
| MEDLINE
| ID: mdl-22749735
4.
J Urol
; 168(1): 202-3, 2002 Jul.
Article
in English
| MEDLINE
| ID: mdl-12050537