[The effect of Wobenzym on the atherogenic potential and inflammatory factors at the rehabilitation stage for patients who have had a myocardial infarct]. / Vliianie vobenzima na aterogennyi potentsial i vospalitel'nye faktory na étape reabilitatsii bol'nykh, perenesshikh infarkt miokarda.

Effects were studied of wobenzyme on atherogenicity of blood serum and immunoinflammatory reactions in patients with myocardial infarction during the rehabilitation stage over six months. The basis therapy when supplemented with wobenzyme was found out to facilitate normalization of the atherogenic potential and to have a positive action on the mediators of the inflammatory process.

[The clinico-immunological indices and characteristics of the thrombocytic link of hemostasis in patients with a history of a myocardial infarct at the rehabilitative stage]. / Kliniko-immunologicheskie pokazateli i nekotorye osobennosti trombotsitarnogo zvena gemostaza u bol'nykh, perenesshikh infarkt miokarca, ne étape reabilitatsii.

There have been conducted immunological investigations and those of designed to study homeostasis secured by thrombocytes in 68 patients with ischemic heart disease, who had survived one or more myocardial infarction in the recovery stages, during which time restoration of their functional capacity and ability to work were becoming clinically apparent. These groups of patients demonstrate appreciable deviations in the immunologic status of the organism, consistent chiefly with the humoral type of events owing to both allergic and anaphylactic reactions. The above alterations occur against the background of T-cellular immunodeficiency, raised levels of B-lymphocytes and a change in the functional state of thrombocytes. During the first six months period of the year the aggregational and adhesive properties begin gradually return to normal.

[Autoimmune processes in patients with different forms of the clinical course of ischemic heart disease]. / Autoimmunnye protsessy u bol'nykh s razlichnymi formami klinicheskogo techeniia ishemicheskoi bolezni serdtsa.

A study of autoimmune processes in 286 patients with different clinical forms of ischemic heart disease revealed a high frequency of antibodies to "healthy myocardium" antigen in patients with non-stable stenocardia and acute myocardial infarction that may indicate acquirement of antigenic properties of the healthy myocardium. Patients with unstable stenocardia also show an increased antibody titer to vascular antigens that indicates the possible role of activation of autoimmune reactions in the mechanisms of destabilization of the clinical course of ischemic heart disease.

[The immunological indices of patients who have had a myocardial infarct]. / Nekotorye immunologicheskie pokazateli u bol'nykh, perenesshikh infarkt miokarda.

The authors carried out immunological examination of 68 patients with ischemic heart disease with a history of one or several myocardial infarctions. The patients showed changes of the immune status, mainly of the humoral type due to allergic reactions caused by immune complexes and also anaphylactic reactions provoked by IgE-antibodies. The above changes occurred against the background of T-cellular immunodeficiency and increased content of B-lymphocytes. Increase of the level of indices of unspecific defence is a manifestation of compensatory reactions directed to elimination of the increased content of circulating immune complexes from the body of the patients.