[Myocardial reaction and lung ventilation response to inhalation of the gaseous hypoxic mixture GGS-10 in patients with rheumatoid arthritis]. / Reaktsiia miokarda i ventiliatsii legkikh na vdykhanie gazovoi gipoksicheskoi smesi GGS-10 u bol'nykh revmatoidnym artritom.

The initial and end parts of the ventricular complex of the ECG and the roentgenopneumopolygraphy data were assayed in 22 patients with rheumatoid arthritis before and after inhalation of the gaseous hypoxic mixture (GGS-10) consisting of 90% of nitrogen and 10% of oxygen. After the inhalation of the mixture the area of the ST-T segment significantly increased as compared with the initial data, mainly in the AVR, V2 and V5 leads of the ECG. In addition, individual features of the changes in respiratory pulmonary function were discovered, which directly correlated with the disease stage.

[Changes in the ECG following a session of regional intra-arterial hyperglycemia]. / Izmenenie EKG posle provedeniia seansa regionarnoi vnutriarterail'noi giperglikemii.

ECG changes after a session of regional intraarterial hyperglycemia (RIH) in 13 patients (the mean age of 49 years) with locally advanced cancer of the tongue, oral mucosa and oropharynx were presented. The time course of ECG resulted from a noticeable decrease in the T wave amplitude or a shift of the ST-T segment below the isoline. The results of quantitative ECG changes were the following. The area of the R, AVR, AVF wave and QRS, AVR, AVF complex was decreased. Besides, a significant diversity of changes of the area of ST-T segment, its increase in AVR and AVF and decrease in the V2 leads were noted in this group of patients. Taking into account the mean age of patients and the negative ECG time course after a RIH session, the necessity of patients' examination (including ECG after a RIH session and, when indicated, a consultation by a cardiologist) was emphasized.

[Evaluation of the functional state of the myocardium before and after drug therapy of thyrotoxicosis]. / Otsenka funktsional'nogo sostoianiia miokarda do i posle medikamentoznoi terapii tireotoksikoza.

Thirty-five patients with grave and medium-grave thyrotoxicosis were subjected to a quantitative analysis of the initial and end part of the ventricular complex of the ECG before and after specific drug therapy. The data obtained were compared with the radionuclide data on the cardiovascular system, the blood content of T3 and T4 and amount of potassium in the body. At the height of the disease the patients manifested a decrease in the output fraction of the left ventricle, stroke volume, minute volume, coefficient of circulation effectiveness, the deceleration of the lung blood flow and a rise of the total peripheral resistance to the blood flow as compared to normal. The treatment brought about a significant reduction of the area of the QRS complex and ST-T segment, as compared to the findings obtained during the acute period, mainly in the II, III, AVR, AVF and V5 leads of the ECG. A direct correlation was established between the blood content of T3 and the area of the ST-T segment in the II, III, AVR and AVF leads. It has been found that intracellular concentration of potassium may have an effect on the ECG changes revealed in the patients.

Impairment of left ventricular kinetics in lymphogranulomatosis with involvement of lymphatic mediastinal nodes.

Echocardiographic examination of 56 patients with lymphogranulomatosis involving lymphatic mediastinal nodes showed in four cases a paradoxical excursion of the interventricular septum and systolic thickening ("isosceles triange") of the posterior left ventricular wall. Clinico-instrumental examination of the patients made it possible to rule out in these subjects the presence of constrictive pericarditis, which had been formerly considered one of the causes of a disturbance of left ventricular kinetics.

[Changes in the ECG ventricular gradient before and after the drug therapy of thyrotoxicosis]. / Izmenenie zheludochkovogo gradienta EKG do i posle medikamentoznoi terapii tireotoksikoza.

In 57 patients with moderate and severe thyrotoxicosis the ventricular ECG gradient was examined. A direct significant correlation between the change in the size and localization of the ventricular gradient and A vector of the T wave was noted, indicating the primary disorder of the myocardial repolarization in these patients. The study on the ventricular gradient projection in humans with thyrotoxicosis allows one to obtain an additional information on electrocardiographic changes in these patients.