ABSTRACT
Hypoparathyroidism (HP) is a syndrome caused by insufficient secretion or weak action of parathormone leading to hypocalciemia (HC) and intermittent tetanus. HP is the most frequent cause of HC but not a single one. HC may present in 30 etiopathogenic variants and, consequently, being a problem for many clinical disciplines. Practical aspects of etiopathogenesis, clinical and laboratory diagnosis and treatment of a hypocalciemic syndrome of different nature are considered.
Subject(s)
Hypocalcemia/etiology , Hypoparathyroidism , Calcium/blood , Calcium/deficiency , Calcium/therapeutic use , Humans , Hypoparathyroidism/classification , Hypoparathyroidism/complications , Hypoparathyroidism/diagnosis , Hypoparathyroidism/etiology , Hypoparathyroidism/therapy , Parathyroid Hormone/metabolism , Syndrome , Tetany/etiologyABSTRACT
Echocardiography was performed in 67 patients with compensated diabetes mellitus (DM) type I and II. No signs of cardiovascular failure were noted. 20 patients have undergone myocardial scintigraphy. The patients were found to have hyperkinetic central hemodynamics resultant in DM type I from tachycardia, high rate of circulatory shortening of myocardial fibers, in DM type II from compensatory myocardial hypertrophy. In both diabetic types the function of myocardial relaxation was deteriorated as indicated by increased end diastolic volume and slow left ventricular relaxation. This evidences for initial cardiac failure. Myocardial scintigraphy registered perfusion defects in all the examinees, more profound in diabetes mellitus type II. The above findings explain the existence of marked coronarogenic and metabolic myocardial defects in DM.
