Engineering Approach to Identifying Patients with Colon Tumors on the Basis of Electrophotonic Imaging Technique Data.

BACKGROUND: Colonic neoplasms are quite a serious problem today. Screening methods play an important role in diagnosing the disease. Colorectal cancer screening is a complex undertaking, having various options, which require a lot of efforts both from the doctor and from the patient, including the use of sedatives and the necessity of the presence of an assistant for some procedures such as colonoscopy. This is why it is very important to find a method by which one can make a diagnosis quickly, easily, and painlessly. METHODS: The ability to identify patients with tumors of the colon using the Electrophotonic Imaging (EPI) technique, as well as using it for differential diagnosis of tumors of the colon by their morphology, size and quantity was investigated. Selection of the most significant parameters of the EPI-graphy for the separation of the control group and the group of patients with tumors of the colon was developed. 137 people were studied with the EPI camera, with ages ranging from 16 to 86 years, including 49 males and 88 females. Based on the results of the colonoscopy and histological findings all subjects were divided into 2 groups: control group of 55 people, 9 males, 46 females; and patients with tumors (benign or malignant) of the colon - 82 people; 40 males and 42 females. Then all subjects were divided into smaller groups based on morphology, size, number of tumors and localization. RESULTS: Based on the identified indicators decision rules to determine the patients with tumors of the colon were constructed. The specificity of the resulting function was 80.0% and sensitivity 75.6%. Decision rule was built as well with logistic regression. The specificity of the resulting function was 78.2% and sensitivity 90.0%. The accuracy of this approach was higher than using discriminant analysis. CONCLUSIONS: The results of this study have proven the ability to identify patients with tumors of the colon using EPI technology, as well as use it for differential diagnosis of tumors of the colon by their morphology, size and quantity. EPI testing is non-invasive, takes less than five minutes, and equipment is relatively cheap and accessible in mass production. This opens up good prospects for further research for implementation as a first step of the screening process. This paper presents the pilot study developing methodological approach to the GDV data processing. That is why we tried different methods of data processing. At the same time we do not pretend to develop a diagnostic method - sample size is too small for this, and other cancer types were not studied. Further research is needed.

[Effect of medications and acupuncture on indicators of a bioenergetigram of bronchial asthma patients]. / Vliianie medikamentoznykh sredstv i akupunktury na pokazateli bioénergogrammy bol'nykh bronkhial'noi astmoi.

AIM: To evaluate the energy informational effects of various treatments in patients with bronchial asthma (BA). MATERIAL AND METHODS: Changes in bioenergograms were analyzed in 139 patients after therapeutical exposures: intravenous prednizolone and dexamethasone, inhaled seretide, fluthicasone propionate, beclomethasone, phenoterol, salmeterol, and salbutamol, the latter drug as tablets, as well as a course treatment with acupuncture. The energy informational effects of pumpan and nitrosorbide were studied in 22 patients with BA concurrent with cor pulmonale and coronary heart disease (CHD). RESULTS: A significant difference was found in the parameters of a bioenergogram depending on the routes of administrations of the drugs and their dosage forms. The greatest and positive changes in the area of the bioenergogram were recorded when using salmeterol and salbutamol, particularly in the nebulization of their solutions, and acupuncture. The intravenous infusion of glucocorticosteroids frequently produced inhibitory effects. In patients with BA concurrent with cor pulmonale and CHD, the positive energy informational effect of pumpan, that differed from that of nitrosorbide, occurred with better ventricular repolarization and alleviated signs of right cardiac overload on ECG. CONCLUSION: The bioenergogram is highly sensitive to changes in the status of patients and it may be used to choose drugs and their combinations, combined drug therapy, and acupuncture on an individual basis. Pumpan is recommended for the treatment of patients with BA concurrent with cor pulmonale.

[Method for gas-discharge visualization and automation of the system of realizing it in clinical practice]. / Metod gazorazriadnoi vizualizatsii i avtomatizirovannaia sistema ego realizatsii v klinike.

The stage of diagnosis is essential in terms of both the choice of the most adequate treatment policy and the monitoring of human responses to various environmental factors, including living and working conditions, conflicts, predisposition to some diseases, etc. To develop new non-invasive automatic procedures that assess the body's condition during minimum interventions into vital functions is of great scientific and practical value. The gas-discharge visualization method is a promising direction in the construction of these procedures.