ABSTRACT
A positive result has been obtained in treating sleep disorders in patients with chronic vascular affections of the brain with using the drugs donormyl and sonnate-KM [symbol: see text]. Donormyl is recommended for use in sleep disturbances (not very prolonged and not profound insomnia) in a 10-day therapeutic course as a first-choice drug.
Subject(s)
Cerebrovascular Disorders/complications , Doxylamine/analogs & derivatives , Doxylamine/therapeutic use , Hypnotics and Sedatives/therapeutic use , Sleep Initiation and Maintenance Disorders/drug therapy , Administration, Oral , Adult , Aged , Aged, 80 and over , Azabicyclo Compounds , Doxylamine/administration & dosage , Female , Humans , Hypnotics and Sedatives/administration & dosage , Male , Middle Aged , Piperazines/administration & dosage , Piperazines/therapeutic use , Sleep Initiation and Maintenance Disorders/complications , Treatment OutcomeABSTRACT
The authors submit results of treatment of patients having suffered from postherpetic pain syndrome (herpetic ganglionitis of the cervical, thoracic, lumbosacral localization, postherpetic intercostal neuralgia, ganglionitis of the trigeminal nerve). In viral diseases, amizone has marked analgetic, antiinflammatory, and immunomodulating effects. The drug is well tolerated by patients, is not associated with side effects under prescribed doses (0.25-0.75 as one dose on a three- or four-times daily schedule during the course of treatment lasting three or four weeks). The drug preparation in question is less effective in the treatment of chronic recurring post-therapeutic intercostal neuralgias, radiculalgia.
Subject(s)
Analgesics, Non-Narcotic/therapeutic use , Herpes Zoster/complications , Pain, Intractable/drug therapy , Adult , Aged , Dose-Response Relationship, Drug , Drug Evaluation , Female , Herpes Zoster/diagnosis , Humans , Neuralgia/drug therapy , Pain, Intractable/diagnosis , Pain, Intractable/etiology , Radiculopathy/drug therapy , TabletsABSTRACT
The authors studied the indices of general hemodynamics in 53 patients with initial manifestations of cerebro-circulatory insufficiency of young and middle age. Young patients suffering of cerebral atherosclerosis and vegetative-vascular dystonia showed a hyperkinetic type of hemodynamics while the middle-aged with atherosclerosis showed the hypokinetic type evidencing abnormal function of autoregulatory mechanisms.