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Clin EEG Neurosci ; 48(3): 217-230, 2017 May.
Article in English | MEDLINE | ID: mdl-27354361

ABSTRACT

Postconcussion syndrome (PCS) has been used to describe a range of residual symptoms that persist 12 months or more after the injury, often despite a lack of evidence of brain abnormalities on magnetic resonance imaging and computed tomography scans. In this clinical case series, the efficacy of quantitative EEG-guided neurofeedback in 40 subjects diagnosed with PCS was investigated. Overall improvement was seen in all the primary (Symptom Assessment-45 Questionnaire, Clinical Global Impressions Scale, Hamilton Depression Scale) and secondary measures (Minnesota Multiphasic Personality Inventory, Test of Variables for Attention). The Neuroguide Traumatic Brain Index for the group also showed a decrease. Thirty-nine subjects were followed up long term with an average follow-up length of 3.1 years (CI = 2.7-3.3). All but 2 subjects were stable and were off medication. Overall neurofeedback treatment was shown to be effective in this group of subjects studied.


Subject(s)
Brain/physiopathology , Electroencephalography , Neurofeedback/physiology , Post-Concussion Syndrome/physiopathology , Adult , Biomarkers/analysis , Electroencephalography/methods , Female , Humans , Magnetic Resonance Imaging/methods , Male , Neuropsychological Tests , Psychiatric Status Rating Scales , Young Adult
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