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1.
Article in Russian | MEDLINE | ID: mdl-10925876

ABSTRACT

The intensity of immunity, depending on immune response variants characterized by the definite composition of the T and B lymphocyte subpopulation in peripheral blood, was studied in 70 practically healthy young children after the primary complex of immunization with adsorbed DPT vaccine. The most stable immune reaction was shown to appear in children with the hyperergic and normoergic variants of immune response to diphtheria and tetanus toxoids, while the reaction to pertussis antigen was essentially weaker both after the second vaccination and after the first revaccination. In children with the hypoergic variant of immune response to all components of adsorbed DPT vaccine the resulting immune reaction was 2.5-3 times weaker than in children of other groups.


Subject(s)
Diphtheria-Tetanus-Pertussis Vaccine/immunology , Adsorption , Antibodies, Bacterial/blood , Antibody Specificity , B-Lymphocytes/immunology , Bordetella pertussis/immunology , Clostridium tetani/immunology , Corynebacterium diphtheriae/immunology , Humans , Immunity, Cellular , Immunization Schedule , Immunization, Secondary/statistics & numerical data , Infant , Statistics, Nonparametric , T-Lymphocytes/immunology
3.
Lab Delo ; (12): 21-3, 1989.
Article in Russian | MEDLINE | ID: mdl-2483194

ABSTRACT

A method for studies of the kinetics of the routine and alternative complement system activation has been developed, consisting in regular scintillation of the red cell count in the test system with the use of the Pikoskel laboratory cell scintillator. A relationship between the rate of the red cell count reduction and the complement system compensatory activity in the examined patients has been demonstrated.


Subject(s)
Complement Activation , Erythrocyte Count , Humans , Kinetics
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