[The influence of circadian rhythms of geomagnetic field variations and the background cosmic radiation on nitric oxide production in human organism].

The circadian rhythms of background gamma-radiation and Ki-indexes of geomagnetic activity (GMF) during August-September 2008, January-February 2010 and March 2011 were studied. The authors show that in summer period the maximum of Ki-indexes and gamma-radiation were at 3 p.m. of local time. In winter these maximums were shifted at more last time. It was suggested that an organism produces the own free radicals as nitric oxide to neutralize radicals from background radiation. They are formed during decay of neutrophiles when GMF-activity falls. On the other side, the production of NO is regulated by melatonin synthesis which has a circadian rhythm.

[The influence of ferromagnetic screening from natural electromagnetic fields on the hematological and toxicogenomic indexes in animals].

The aim of the study was to reveal during 45 days consequences of ferromagnetic screening (FS) on the hematological and toxicogenomic indexes in rats. An express-method of nucleiod DNA content in blood by help fluorescent indication was used for alive quantitative evaluation of the toxicogenomic effects. The FS for both gender rats during 48 hrs resulted in both decreased magnetic field by 4-10 microT1 and leucopenia by 14 day of experiment. The aneu-/polyploidy index in male leucocytes was increased by 48 hr of FS and lasted out to 12-28 days after the screen removal. The leukocyte apoptosis was enhanced in female in 48 hrs only after the FS start.

[The influence of geomagnetic field variations on the pineal gland circadian activity].

Daily changes of geomagnetic field (GMF) of the Russian northwest region were studied in different seasons of years with high and low sun activities. It was shown that Ki-indexes of GMF-activities had minimal values at 4-5 h of UT, as a peak of maximum was at 20-21 h of UT in winter but in summer it shifted to 14-15 h UT. It has been suggested that the level of GMF in the environment influences the processes with nitric oxide participation, which effects on the melatonin production by pineal gland. GMF, along with illumination, take part in circadian activity of pineal gland.

[The influence of geomagnetic variations on the formation of nitric oxide in exhaled air in human].

The content of nitric oxide in exhaled air in healthy persons has been studied. It was shown that nitric oxide in exhaled air is formed from saliva nitrite due to the nitrite reductase activity of mouth cavity microflora. A relationship between the nitric oxide level and age, arterial pressure, and geomagnetic field indices was established. It was shown that the level of nitric oxide diminishes with age. A negative correlation between the nitric oxide content in exhaled air and arterial pressure (systolic and diastolic) was found. It was assumed that nitric oxide from the mouth can penetrate into the lungs and then to the blood where it can influence the vessel tonus. It was shown that the negative relationship took place between nitric oxide level in the air and Ki-indices of geomagnetic field on the day of measurement or the day preceding the measurement. The data obtained suggest that nitric oxide is involved in processes causing infarcts and insults in periods of magnetic storms.

[The hemathological reactions in rats after partial screening from natural electromagnetic fields].

The influence of partial screening of EMF on the composition of white blood cells was studied in the experiments on rats. Two kinds of copper rings were used in these experiments: individual for each rat and common for the cage. It was shown that inside the ring the composition of blood cells was changed--in 3-5 hours the number of granulocytes increased and in 24 hours it restored to the initial level. The effect was more expressive in the experiments using individual rings. In control groups the experiment with plastic rings didn't reveal this effect. It was presumed that EMF prevented the decay of granulocytes. It leads to the increase of their guantity. It was revealed that there was a positive correlation between Ki-indexes of geomagnetic field (GMF) in 1-2 days before the experiments and the number of granulocytes in rats during 1995-2002. Ki-indexes reflect the degree of GMF disturbance. During magnetic storms the spreading of EMF in radio-frequency range changes. It was presumed that the effect of partial screening of EMF of rats and the activity of magnetic storms are similar in their influence on the composition of white blood cells of rats.

[The influence of geomagnetic field on blood leukocyte radiosensitivity and gender determination in humans]. / Vliianie geomagnitnogo polia na radiochuvstvitel'nost' leikotsitov krovi i determinatsiiu pola cheloveka.

The gender and age features of the geomagnetic field (GMF) influence (K-indexes) on the leukocyte radiosensitivity (S) in human blood in case of normal and enhanced levels of metal-ecotoxicants (Pb, Cd, Hg, Mn, Zn, Cu) in blood was studied, as well as the impact of the GMF intensity alterations on the child gender determination. In the whole studied population (n = 244) it was observed a negative relationship between S- and K-indexes. It was shown that the most changes of blood leukocyte radiosensitivity depended on the GMF oscillations in men older than 45 years. In case of metal-ecotoxicant concentrations in blood near normal level there were observed significant relationships between S- and K-indexes, which was infringed by more than 2-fold excess of these toxicant concentrations in blood. Retrospective analysis showed that in case of the GMF intensity enhancement in the conception moment the girls were born mostly, and in case of the lowering--the boys were.