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1.
BMC Neurol ; 15: 131, 2015 Aug 05.
Article in English | MEDLINE | ID: mdl-26242758

ABSTRACT

BACKGROUND: Anxiety, depression and functional impairments are commonly reported by persons with multiple sclerosis (PwMS) but no data, to our knowledge, has emerged from an Arab Islamic population. The study aims to investigate the prevalence of anxiety, depression and related disabilities among PwMS attending tertiary care in Sultan Qaboos University Hospital (SQUH), one of the urban hospitals in Oman. METHODS: Consecutive and consenting PwMS (n = 57) and healthy subjects (n = 53) completed the following measures: Hospital Anxiety and Depression Scale (HADS) which was used to measure anxiety (cut-point >7) and depression (>7); and Expanded Disability Status Scale (EDSS) to measure the level of disability (≥5). Characteristics such as socio-demographic and clinical variables were also explored. RESULTS: Fifty seven subjects with multiple sclerosis (MS) met the inclusion criteria. The majority of them were females who were 40 years old or younger and the majority were employed and unmarried. Approximately 86 % of the participants were using beta interferon, 96 % scored ≥5 in EDSS. MS of the Relapsing-Remitting type constituted the majority of the cohort (94 %). Approximately 35 % and 51 % endorsed symptoms of anxiety and depression respectively. The MS group scored significantly higher than controls on HADS measurements of depression and anxiety. CONCLUSION: Disability and symptoms of anxiety and depression are common among the PwMS attendees of tertiary care hospital in Oman. Such psychosocial variables have been largely unreported emerging from non-western populations. As these variables are strong indicators of the burden of MS, resolute effort is needed to address such psychosocial dysfunctions in the algorithms of care for PwMS in the Arab Islamic part of the world.


Subject(s)
Anxiety/epidemiology , Depression/epidemiology , Multiple Sclerosis/epidemiology , Adult , Anxiety/psychology , Case-Control Studies , Cross-Sectional Studies , Depression/psychology , Disability Evaluation , Female , Humans , Immunologic Factors/therapeutic use , Interferon-beta/therapeutic use , Male , Middle Aged , Multiple Sclerosis/drug therapy , Multiple Sclerosis/psychology , Oman/epidemiology , Prevalence , Tertiary Care Centers , Urban Population
2.
Pak J Biol Sci ; 17(10): 1098-105, 2014 Oct.
Article in English | MEDLINE | ID: mdl-26027153

ABSTRACT

The elderly population is increasing worldwide and it has been suggested that senior citizens will continue to constitute the bulk of the population in many countries. Nutritional status of senior citizens are adversely affected by their frailty, chronic condition and declining cognitive functioning. Conversely, malnourished elderly further deteriorate their frailty, chronic disease and cognitive functioning. The aim of this review article is to recognize the importance of nutritional assessment of elderly population particularly those with cognitive impairment. First part is to highlight characteristic cognitive impairment among senior citizens and the second one highlight t he background in which malnutrition is a factor that leads to increased risk of morbidity and mortality in the elderly. This review also highlight salgorithms for safeguarding nutritional status among senior citizen and focuses on importance of nutritional screening, assessment and early intervention for safeguarding further deterioration of elderly who are likely to prone to cognitive impairment.


Subject(s)
Aging/psychology , Cognition Disorders/diagnosis , Cognition , Geriatric Assessment , Malnutrition/diagnosis , Nutrition Assessment , Nutritional Status , Age Factors , Aged , Aged, 80 and over , Cognition Disorders/physiopathology , Cognition Disorders/psychology , Cognition Disorders/therapy , Frail Elderly , Humans , Malnutrition/physiopathology , Malnutrition/psychology , Malnutrition/therapy , Middle Aged , Nutritional Support , Predictive Value of Tests , Risk Factors , Treatment Outcome
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