1.
J Bacteriol
; 175(19): 6113-7, 1993 Oct.
Article
in English
| MEDLINE
| ID: mdl-8407783
ABSTRACT
The kinetics of processing of glyceride-modified prolipoprotein that accumulated in globomycin-treated Escherichia coli has been found to be affected by sec mutations, i.e., secA, secE, secY, secD, and secF, and by metabolic poisons which affect proton motive force (PMF). The effect of sec mutations on processing of glyceride-modified prolipoprotein in vivo was not due to a secondary effect on PMF. Neither a secF mutation nor metabolic poisons affected the processing of previously accumulated proOmpA protein in vivo, suggesting that the requirements for functional sec gene products and PMF are specific to the processing of lipoprotein precursors by signal peptidase II.
Subject(s)
Bacterial Outer Membrane Proteins/metabolism , Escherichia coli Proteins , Escherichia coli/metabolism , Genes, Bacterial , Lipoproteins/biosynthesis , Peptides , Protein Precursors/metabolism , Protein Processing, Post-Translational , Anti-Bacterial Agents/metabolism , Arsenates/pharmacology , Azides/pharmacology , Bacterial Outer Membrane Proteins/biosynthesis , Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology , Energy Metabolism/drug effects , Escherichia coli/drug effects , Escherichia coli/genetics , Genotype , Kinetics , Methionine/metabolism , Mutagenesis , Proline/metabolism , Sodium Azide , Sulfur Radioisotopes , Tritium
2.
Lijec Vjesn
; 106(9): 353-7, 1984 Sep.
Article
in Croatian
| MEDLINE
| ID: mdl-6503599