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Trans R Soc Trop Med Hyg ; 99(2): 128-41, 2005 Feb.
Article in English | MEDLINE | ID: mdl-15693148

ABSTRACT

Twenty-four distinct outbreaks of probable chikungunya (CHIK) etiology were identified throughout Indonesia from September 2001 to March 2003, after a near 20-year hiatus of epidemic CHIK activity in the country. Thirteen outbreak reports were based on clinical observations alone, and 11 confirmed by serological/virological methods. Detailed epidemiological profiles of two investigated outbreaks in Bogor and Bekasi are presented. Human sera were screened using an ELISA for IgM and IgG anti-CHIK antibodies. Additionally, reverse transcriptase PCR and virus isolation were attempted for virus identification. The mean age of cases was 37 +/- 18 years in Bogor and 33 +/- 20 years in Bekasi. There was no outstanding case-clustering, although outbreak-affected households were observed to be geographically grouped within villages. The attack rates in Bogor and Bekasi were 2.8/1000 and 6.7/1000 inhabitants respectively. Both outbreaks started in the rainy season following increased Aedes aegypti and A. albopictus densities.


Subject(s)
Alphavirus Infections/epidemiology , Chikungunya virus/isolation & purification , Disease Outbreaks , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Alphavirus Infections/immunology , Antibodies, Viral/blood , Chikungunya virus/immunology , Child , Child, Preschool , Humans , Immunoglobulin G/blood , Immunoglobulin M/blood , Indonesia/epidemiology , Middle Aged , RNA, Viral/analysis , Reverse Transcriptase Polymerase Chain Reaction/methods , Risk Factors , Seasons
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