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Urol Nefrol (Mosk) ; (4): 32-5, 1995.
Article in Russian | MEDLINE | ID: mdl-7571199

ABSTRACT

94 patients with obstructive urination due to benign prostatic hyperplasia received finasteride (proscar), inhibitor of 5 alpha-reductase, in a single dose 5 mg and terazosine, alpha 1 adrenoblocker, in a daily dose of 9.7 mg/day. The follow-up averaged 16.1 months. As shown by overall score of the symptoms and quality of life, rectal and ultrasonic examinations, uroflowmetry, the prostate decreased by 17%, on the average in 72% of the patients. Subjectively, urination has also improved. Maximal flow rate elevated by 55% in the majority of patients. Combination of finasterine with terazosine is well tolerated and proved optimal as a conservative therapy in patients with obstructive urination as a result of benign prostatic hyperplasia.


Subject(s)
5-alpha Reductase Inhibitors , Adrenergic alpha-Antagonists/therapeutic use , Enzyme Inhibitors/therapeutic use , Finasteride/therapeutic use , Prazosin/analogs & derivatives , Prostatic Hyperplasia/drug therapy , Aged , Chronic Disease , Delayed-Action Preparations , Drug Therapy, Combination , Humans , Male , Middle Aged , Prazosin/therapeutic use , Remission Induction , Time Factors
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