[The ecological aspects of the epidemiology of hemorrhagic fever with renal syndrome in the south of the Far East in Russia]. / Ekologicheskie aspekty épidemiologii gemorragicheskoi likhoradki s pochechnym sindromom na iuge Dal'nego Vostoka Rossii.

The data on the relationship between the epizootic process in the population of mice (the source of Hantavirus infection) and the seasonal manifestations of morbidity in hemorrhagic fever with renal syndrome (HFRS) in the southern region of the Russian Far East are presented. The asynchronous course of the epizootic process in the population of rodents causes irregularity in the spread of HFRS in the region and periodicity in the appearance of foci. Seasonal rises in HFRS morbidity coincide with the activity of the epizootic process in the population of mice: spring-summer rises with an increase in the number of infected rodents in the populations of large Japanese field mice and autumn-winter rises in voles.

[The role of Hantaan virus serotypes in the etiology of hemorrhagic fever with renal syndrome in the Far East of the USSR]. / Izuchenie roli serotipov khantavirusa v étiologii gemorragicheskoi likhoradki s pochechnym sindromom na Dal'nem Vostoke SSSR.

The employment of two serological tests (indirect fluorescence antibody technique and neutralization test) demonstrated the leading role of Hantaan virus serotype 1 strains isolated from field mice in the pattern of the incidence of hemorrhagic fever with renal syndrome (HFRS). Proofs of the etiological importance of strains of serotypes 3 and 5 occurring in brown rats and Cl. rufocanus were obtained. No data on any association of human HFRS cases with strains of serotype 4 isolated from reed voles could be demonstrated.

[Serologic diagnosis of mild, unclear and asymptomatic forms of hemorrhagic fever with renal syndrome]. / Serologicheskaia diagnostika legkikh, stertykh i bessimptomnykh form gemorragicheskoi likhoradki s pochechnym sindromom.

The use of the serological method (the indirect fluorescent antibody test) for the examination of 255 persons coming in contact with patients having hemorrhagic fever with the renal syndrome (HFRS) in the foci of this infection where outbreaks of group infection had been registered made it possible to detect mild, unclear and asymptomatic forms of HFRS in 17.7-20.9% of cases. The simultaneous titration of 317 serum samples with two antigens revealed that HFRS virus of serotype 1, similar to strain Hantaan from Korea, may cause, besides the classical forms of the disease, the development of mild and asymptomatic forms of this infection.

[Reservoirs of the causative agent of hemorrhagic fever with renal syndrome in Maritime Territory foci]. / Rezervuary vozbuditelia gemorragicheskoi likhoradki s pochechnym sindromom v ochagakh Primorskogo kraia.

Examinations of 6362 small mammals of 18 species revealed the main reservoirs of the causative agent of hemorrhagic fever with the renal syndrome (HFRS) in foci of the Primorsky Krai, and demonstrated the importance of individual species in the epidemiology of the infection. Data on the circulation in the region of antigenically different serotypes of HFRS virus are presented.

[Hemorrhagic fever with a renal syndrome in the Maritime Territory]. / Gemorragicheskaia likhoradka s pochechnym sindromom v Primorskom krae.

The sporadic character of the occurrence of hemorrhagic fever with the renal syndrome in the Primorye Territory has been established. Three rodent species have been found to be spontaneously infected with the causative agent of this disease. Antibodies in patients with this disease are detected at its early stages and persist for a long time after convalescence. The possibility of the formation of a contingent immune to hemorrhagic fever, due to the persons who have had mild and asymptomatic forms of this infection has been shown.