[Concentration of cyclic adenosine-3',5'-monophosphate in the tissues and its excretion in the urine of rats during ontogenesis]. / Vmist tsyklichnoho adenozyn-3',5'-monofosfatu v tkanynakh i ekskretsiia ioho z secheiu u shchuriv v ontohenezi

The intracellular content of cyclic adenosine 3',5'-monophosphate (cAMP) in the liver and epididymal fat as well as excretion of cAMP with urea were studied in rats at the age of 1, 3, 12 and 24 months. No statistically significant age changes were found in the intracellular content of cAMP in the tissues. A decreases in the intensity of cAMP excretion with urea in the 12-month rats as compared to the one-month ones is statistically significant.