ABSTRACT
The use of spirulina and its efficiency have been studied in a comparative aspect as a systemic biocorrector, in a combined treatment of tuberculosis in 26 children. It has been ascertained that application of spirulina as a pathogenetic means of remediation permits shortening the intoxication syndrome regression time, reducing the frequency of adverse reactions in administering antituberculous preparations.
Subject(s)
Antitubercular Agents/therapeutic use , Bacterial Proteins/therapeutic use , Phytotherapy/methods , Tuberculosis, Pulmonary/drug therapy , Antitubercular Agents/administration & dosage , Antitubercular Agents/adverse effects , Bacterial Proteins/administration & dosage , Bacterial Proteins/adverse effects , Child , Drug Administration Schedule , Drug Therapy, Combination , Humans , Mycobacterium tuberculosis/isolation & purification , Spirulina , Streptomycin/administration & dosage , Streptomycin/therapeutic use , Time Factors , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/physiopathologyABSTRACT
As high as 12.4% of children suffering from tuberculosis are readmitted, rural children are more frequently readmitted (18.0 versus 7.2%, p < 0.01), children having tuberculosis (10.9%) and nonspecific pathology (1.5%). Among the children readmitted for tuberculosis, 75.9% had exacerbations which provoke infectious diseases in 18.2%. In 72.7% of cases, the cause of readmission was premature discharge due to their parents' noncompliance.
Subject(s)
Patient Readmission , Tuberculosis/therapy , Age Factors , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Sex Factors , Tuberculosis, Lymph Node/therapy , Tuberculosis, Pulmonary/therapyABSTRACT
The paper deals with the examination of the state of health of children treated at tuberculosis sanatoria of republican and local importance. At present the tuberculosis sanatoria for children are not considered any more to be strickly uniprofile. The emphasis of their activities is aimed at conducting controlled chemotherapeutic prevention measures among children with small attenuating forms of tuberculosis as well as among those who belong to high risk groups in relation to tuberculosis including concurrent bronchopulmonary diseases of nonspecific etiology.
Subject(s)
Adolescent Medicine/standards , Child Health Services/standards , Health Resorts/standards , Hospitals, Pediatric/standards , Hospitals, Special/standards , Tuberculosis, Pulmonary/therapy , Adolescent , Child , Child Health Services/organization & administration , Hospitals, Pediatric/organization & administration , Hospitals, Special/organization & administration , Humans , UkraineABSTRACT
Computed tomography (CT) of the chest organs was used in a comprehensive examination of 19 children and adolescents with spherical and cavitary formations in their lungs and mediastinum. Comparative analysis of the results obtained by means of routine X-ray examination and CT of the chest organs of the children and adolescents with spherical and cavitary formations in their lungs revealed that CT greatly improved their differential diagnosis. CT provides valuable additional data and is an optimum X-ray method for differential diagnosis of spherical and cavitary formations in children and adolescents.
Subject(s)
Tomography, X-Ray Computed , Tuberculosis, Pulmonary/diagnostic imaging , Adolescent , Cysts/diagnostic imaging , Diagnosis, Differential , Female , Humans , Lung Abscess/diagnostic imaging , Lung Diseases/diagnostic imaging , Lung Neoplasms/diagnostic imagingABSTRACT
Seventy-eight tuberculin-positive schoolchildren at the age of 7 to 15 years from tuberculosis foci living in special institutions of the sanatorium type were subjected to immunological examination. The control group included 22 noninfected children of the same age. Persons with lower counts of T-lymphocytes and their decreased functional activity, unbalance in their subpopulation composition and positive immunospecific responses to tuberculin predominated among the schoolchildren subjected to the examination. The state of the B-lymphocyte system changed insignificantly. It was concluded that persons with markedly suppressed cellular immunity be treated with immunomodulating agents during the chemoprophylaxis course.
Subject(s)
Disease Reservoirs , Tuberculosis, Pulmonary/immunology , Adolescent , Antibody Formation/immunology , Child , Humans , Immunity, Cellular/immunology , Immunologic Tests , T-Lymphocytes/immunology , Tuberculosis, Pulmonary/diagnosisABSTRACT
The time course of tuberculin reactions during isoniazid treatment was studied on 10 guinea pigs with experimental tuberculosis. Linear, temperature and histological characteristics of papules were investigated. Thermographic estimation of papules was performed with cholesteric liquid crystal films. For pathohistological examination a new histochemical method developed at the Kiev Research Institute of Phthisiology and pulmonology on the basis of trimethine dyes of the oxanol class of organic solvents (with PK-144) was used along with the routine procedures. A decrease in the temperature gradient (difference of temperatures over papules and the symmetric areas of the skin on the other side of the animal body) was stated irrespective of the papule linear size. The thermographic method for estimating tuberculin reactions based on pathophysiological processes in papules during isoniazid treatment for 2.5 months proved to be a finer procedure for evaluating tuberculin papules than measuring their linear size.
