Analysis of tensiograms of cerebrospinal fluid with a kinetic model.

We develop a model for estimation of the parameters of dynamic tensiometry of biological fluids based on equations of formal chemical kinetics. The model considers diffusion of low- and high-molecular compounds and conformational restructuring of these compounds in the surface layer. This model was tested on cerebrospinal fluid from patients with meningitis. Some correlations between the parameters of tensiometric curves and protein, chloride, neutrophil, and lymphocyte content in the liquor are detected.