Latent structure and measurement invariance of the Depression Self-Rating Scale for Children across sex and age.

Measurement tools from which valid interpretations can be made are critical for assessing early emerging depressive symptoms, as depressive symptoms in childhood are associated with increased risk for early-onset depressive disorder, recurrence, suicidality, and other psychopathology. The Depression Self-Rating Scale for Children (DSRS) is a widely used self-report scale assessing youth depressive symptoms. The relatively few studies investigating the DSRS' latent structure have yielded mixed results, and measurement invariance (MI) based on sex and age has not been examined. We examined the factor structure and MI of the DSRS across sex and age in a community sample of 6-9-year-olds (N = 352; Mage = 7.57 years, SD = .70). Consistent with the largest prior structural study of the DSRS, a two-factor structure, with factors reflecting elevated negative affect (NA) and low positive affect (PA), showed strong model fit. Although this structure was consistent across sex and age (i.e., configural invariance), loadings of DSRS items varied across sex and age (i.e., metric noninvariance). Allowing the loadings of items contributing to noninvariance to vary across groups improved model fit. Implications for the clinical and research utility of the DSRS and suggestions for future research are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Assessing the dominance behavioral system in early childhood using observational methods.

BACKGROUND: The dominance behavioral system (DBS) is a biologically based system that underpins individual differences in motivation for dominance and power. However, little is known about the DBS in childhood. In order to make strong claims about the DBS's trait-like properties and predictive validity, a clearer understanding of its early development is required. PARTICIPANTS AND PROCEDURE: In a pilot study aimed at developing a behavioral coding system for dominance, a key facet of the DBS, we collected and coded observational data from 58 children, assessed at ages 3 and 5-6. These data were examined in conjunction with measures of child temperament via observational measures, and symptoms of psychopathology. RESULTS: Dominance was moderately stable in early childhood to a degree comparable to other early child temperament traits. Consistent with the study hypotheses, boys were more dominant than girls, and dominance was negatively associated with children's behavioral inhibition, effortful control, and internalizing symptoms. CONCLUSIONS: These results provide initial support for the validity and developmental sensitivity of an objective coding system for assessing facets of the DBS in early childhood. Ultimately, the use of this coding system will facilitate future studies of how early DBS predicts psychological adjustment later in life.

Early childhood impulsivity and parenting predict children's development of externalizing psychopathology.

Parenting and child impulsivity are consistent predictors of children's externalizing symptoms; however, the role of the range of parenting (i.e., variation in parenting across contexts), and its interactions with child impulsivity, are poorly understood. We examined whether characteristic parenting practices and parenting range predicted the course of externalizing symptoms in 409 children (Mage = 3.43 years at baseline, 208 girls) across ages 3, 5, 8, and 11. We assessed parent positive affectivity (PPA), hostility, and parenting structure at child age 3 using three behavioral tasks that varied in context, examining range by modeling a latent difference score for each parenting dimension. Greater PPA range, mean structure, and parenting structure range all predicted fewer symptoms at age 3 for children with higher impulsivity. Lower mean hostility predicted fewer symptoms at age 3 for children with lower impulsivity. Greater PPA, and smaller PPA range, predicted a decrease in symptoms for children higher in impulsivity. Lower hostility range predicted a decrease in symptoms for children with lower impulsivity but predicted maintaining symptoms for children with higher impulsivity. Results demonstrate the differential roles average parenting practices and parenting range play in the development of child externalizing psychopathology, especially in the context of child impulsivity.

Structure of Pathological Personality Traits Through the Lens of the CAT-PD Model.

Personality pathology is increasingly conceptualized within hierarchical, dimensional trait models. The Comprehensive Assessment of Traits Relevant to Personality Disorders (CAT-PD) is a pathological-trait measure with potential to improve on currently prevailing instruments because it has wider content coverage; however, its domain-level structure, which is of scientific and clinical interest, is not established. In this study, we investigated the structure and construct validity of the CAT-PD's domain level to facilitate wider use of the measure. We estimated five- and six-factor models with exploratory factor analysis in a pooled sample of eight independent subsamples (N = 3,987) and found that both models fit the data well; each had interpretable factors that were invariant across gender, sample type, and Black/White racial groups; and the factors had good convergent validity with other measures of maladaptive traits, Big Five personality, and interpersonal problems. Our results support the validity of the CAT-PD for assessing multiple levels of the pathological trait hierarchy.

Associations Between Children's Telomere Length, Parental Intrusiveness, and the Development of Early Externalizing Behaviors.

Shorter telomeres mark cellular aging and are linked to chronic stress exposure as well as negative physical and psychological outcomes. However, it is unclear whether telomere length mediates associations between early stress exposure and later externalizing problems, or whether boys and girls differ in pathways to these concerns. We therefore examined associations between telomere length, early stress via negative caregiving, and children's externalizing symptom development over time in 409 three-year-old children and their parents. Telomere length mediated the association between early parental intrusiveness and later rule-breaking behavior; however, this association was moderated by children's biological sex such that parent intrusiveness was related only to boys' rule-breaking. Findings support the notion that children's telomere length may mark individual differences in responses to negative early caregiving, and highlight a potential mechanism contributing to the development of rule-breaking problems in boys.

The Development of Preliminary HiTOP Internalizing Spectrum Scales.

As part of a broader project to create a comprehensive self-report measure for the Hierarchical Taxonomy of Psychopathology consortium, we developed preliminary scales to assess internalizing symptoms. The item pool was created in four steps: (a) clarifying the range of content to be assessed, (b) identifying target constructs to guide item writing, (c) developing formal definitions for each construct, and (d) writing multiple items for each construct. This yielded 430 items assessing 57 target constructs. Responses from a heterogeneous scale development sample (N = 1,870) were subjected to item-level factor analyses based on polychoric correlations. This resulted in 39 scales representing a total of 213 items. The psychometric properties of these scales replicated well across the development sample and an independent validation sample (N = 496 adults). Internal consistency analyses established that most scales assess relatively narrow forms of psychopathology. Structural analyses demonstrated the presence of a strong general factor. Additional analyses of the 35 nonsexual dysfunction scales revealed a replicable four-factor structure with dimensions we labeled Distress, Fear, Body Dysmorphia, and Mania. A final set of analyses established that the internalizing scales varied widely-and consistently-in the strength of their associations with neuroticism and extraversion.

Preliminary Scales for ICD-11 Personality Disorder: Self and Interpersonal Dysfunction Plus Five Personality Disorder Trait Domains.

The ICD-11 personality disorder model is the first fully dimensional assessment of personality pathology. It consists of a personality disorder (PD) dysfunction-severity dimension, which encompasses both self- and interpersonal dysfunction, and six optional qualifiers for five prominent personality traits-Negative Affectivity (NA), Detachment (DET), Dissociality (DSL), Disinhibition (DSN), and Anankastia (ANK)-plus a borderline pattern that is defined by the criteria of DSM-IV borderline PD. This article reports on the development of a new self-report measure to assess self- and interpersonal dysfunction and the five trait qualifiers. It is the first comprehensive measure of the ICD-11 PD model in that (a) it is the only one to include both PD dysfunction-severity as well as trait scales and because (b) it is based on the Clinical Description and Diagnostic Guidelines, which are more detailed than the "statistical" model description that is currently on the ICD-11 website. The authors wrote 992 items and then reduced the pool to 300 items by eliminating redundancy and selecting the consensus best few items for each subconstruct. Data were collected using an online sample of 383 Prolific workers. Using exploratory factor analysis, seven domain scales were developed, each of which contained two to four scales assessing components of the domain. These preliminary scales' psychometrics were excellent, as were the domains' and their components' convergent and discriminant validity, with a few generally minor exceptions. Structural analyses at the component level revealed a three-factor structure consisting of two moderately correlated Internalizing factors, one centered on Self Dysfunction with two NA components and a DSN component (Distractibility) and the other on Interpersonal Dysfunction with DET and ANK components; as well as an Externalizing factor with DSL and a DSN component (Reckless Impulsivity) that was uncorrelated with the other two factors. Two aspects of the results in particular are striking: (1) ANK was not the opposite end of a DSN dimension, but rather contributed to an Internalizing Interpersonal Dysfunction dimension and (2) DSN had both an Internalizing and an Externalizing component. Implications of the findings and study limitations are discussed.

Child sex moderates the relationship between cortisol stress reactivity and symptoms over time.

BACKGROUND: Past work suggests that individual differences in stress reactivity have implications for the development of psychopathology; in particular, females' stress reactivity appears more closely tied to internalizing symptoms than males' reactivity. Conversely, males who are under-reactive to threat may be at risk for externalizing problems. However, little is known about when such differences may emerge, although this knowledge could have implications for early prevention. METHODS: Cortisol reactivity to a laboratory stressor was assessed in 409 three-year-old children (201 boys), along with parent-reported children's internalizing (anxiety and depression) and externalizing (oppositional-defiant and attention problems and hyperactivity) symptoms. Parent-reported symptoms were re-collected at child ages 5 (N = 379) and 8 (N = 364). Multilevel modelling was used to investigate whether the relationship between cortisol reactivity and symptoms differed between boys and girls over time. RESULTS: Girls with lower cortisol reactivity showed a negative association between depressive symptoms and time, while girls with higher reactivity showed no such association. No interaction between sex and cortisol reactivity was found for anxious symptoms. Boys with higher cortisol reactivity showed a negative association between symptoms and time, while boys with lower cortisol reactivity showed no such association. Time and ADHD symptoms were unrelated for boys, regardless of their cortisol reactivity. CONCLUSIONS: Findings suggest that the implications of stress reactivity indexed via cortisol vary for boys and girls, as well as for different symptom manifestations.

Parenting differentially influences the development of boys' and girls' inhibitory control.

Effortful control (EC) has important implications for children's development. While both child sex and parenting are related to child EC, and while a literature shows early sex differences in children's responses to care, interactions between care and child sex in predicting EC are not well understood. We therefore examined associations between child sex and early caregiving as predictors of children's development of a specific aspect of EC, inhibitory control (IC). A community sample of 406 three-year-old children and their caregivers completed behavioural tasks and observational measures of parenting and IC, and children were re-assessed for IC at age 5. Results showed that early care influenced change in IC over time, although caregiving was a more important influence on boys' IC than girls; specifically, differences in boys' and girls' IC at age 5 were modest when parenting was positive. The implications of a better understanding of sex differences in associations between parenting and the development of IC in early childhood are discussed. Statement of contribution What is already known on this subject? While sex differences in reactivity to early care in the development of externalizing symptoms have been explored, very little is known about such differences in children's early-emerging effortful control. What does this study add? Using a longitudinal design and independent, laboratory methods of assessing study constructs, we provide new information showing that early care appears to differentially influence boys' development of inhibitory control, a key aspect of effortful control, in early childhood.

Catechol-O-Methyltransferase gene (val158met) polymorphisms and anxious symptoms in early childhood: The roles of hypothalamus-pituitary-adrenal axis reactivity and life stress.

Individual differences in hypothalamus-pituitary-adrenal (HPA) axis reactivity to stress (measured via salivary cortisol) have been widely implicated in the etiology of internalizing problems such as depression and anxiety. Literature suggests that stress during early childhood is an important source of contextual risk although its effects may be moderated by polymorphisms of neurotransmitter genes. The COMT val158met is one such polymorphism, and literature documents its link to internalizing problems. To extend these findings, and to better understand the role of this polymorphism in developmental risk, we investigated links between the val158met polymorphism and early-age cortisol response. Additionally, we investigated whether cortisol reactivity mediated the link between COMT and emerging internalizing symptoms. The study was conducted in a community sample of 409 preschoolers. Saliva samples were collected pre-stress task (baseline) and every 10min post-stress task for one-hour to asses cortisol response. Child anxious and depressive symptoms were tabulated based on parent-reports. Markers of early childhood stress included marital discord, socio-economic status and the UCLA Life Stress Interview. Findings indicated that the val158met polymorphism is associated with childhood cortisol response (p<0.05). A gene-environment interaction between val158met and life stress also predicted child anxiety symptoms (p<0.01). Finally, cortisol response mediated the main-effect of val158met on child anxiety symptoms (pathway ps<0.05). Analyses suggest that COMT val158met moderates the influence of early life stress on preschool-age symptoms of anxiety. Additionally, cortisol reactivity acts as a mechanistic mediator of the main-effect of COMT genotype on child anxious symptoms.

Higher and Lower Order Factor Analyses of the Temperament in Middle Childhood Questionnaire.

The Temperament in Middle Childhood Questionnaire (TMCQ) is a widely used parent-report measure of temperament. However, neither its lower nor higher order structures has been tested via a bottom-up, empirically based approach. We conducted higher and lower order exploratory factor analyses (EFAs) of the TMCQ in a large ( N = 654) sample of 9-year-olds. Item-level EFAs identified 92 items as suitable (i.e., with loadings ≥.40) for constructing lower order factors, only half of which resembled a TMCQ scale posited by the measure's authors. Higher order EFAs of the lower order factors showed that a three-factor structure (Impulsivity/Negative Affectivity, Negative Affectivity, and Openness/Assertiveness) was the only admissible solution. Overall, many TMCQ items did not load well onto a lower order factor. In addition, only three factors, which did not show a clear resemblance to Rothbart's four-factor model of temperament in middle childhood, were needed to account for the higher order structure of the TMCQ.

The Serotonin Transporter Promoter Variant, Stress, and Attentional Biases in Middle Childhood.

Although evidence suggests that 5-HTTLPR variants may shape risk for depression, the influence is likely complex, and involves effects on endophenotypes. We examined associations between 5-HTTLPR and biases in attention to affective stimuli in a sample of girls and a sample of both boys and girls. Children with at least one short (S) variant of the 5-HTTLPR polymorphism had lower positive attentional bias scores in both samples. This association was qualified by an interaction with stress in one sample, such that links between the S allele and decreased positive attentional bias was significant only when life stress was elevated. This difference in findings between the two samples was explained by sex differences in samples; the GXE interaction was significant only in boys. Findings are discussed in the context of sex differences in GXE.

Higher- and lower-order factor analyses of the Children's Behavior Questionnaire in early and middle childhood.

The Children's Behavior Questionnaire (CBQ; Rothbart, Ahadi, & Hershey, 1994), a 195-item parent-report questionnaire, is one of the most widely used measures of child temperament, with previous analyses of its scales suggesting that 3 broad factors account for the overarching structure of child temperament (Rothbart, Ahadi, Hershey, & Fisher, 2001). However, there are no published item-level factor analyses of the CBQ, meaning that it is currently unclear whether items clearly load onto CBQ scales as proposed by its developers. Additionally, although the CBQ is intended to cover a broad window of development (i.e., ages 3-7), little is known about whether the structure of the CBQ differs depending on child age. The present study used a bottom-up approach to examine the lower- and higher-order structure of the CBQ in a large community sample of children at ages 3 (N = 944) and 5/6 (N = 853). Item-level exploratory factor analyses (EFAs) identified 88 items at age 3 and 87 items at age 5/6 suitable (i.e., with loadings ≥.40) for constructing lower-order factors. Of the lower-order factors derived at ages 3 and 5/6, fewer than half resembled original CBQ scales (Rothbart et al., 1994, 2001). Higher-order EFAs of the lower-order factors suggested that a 4-factor structure was the best fit at both ages 3 and 5/6. Thus, results indicate that a substantial number of CBQ items do not load well on a lower-order factor and that more than 3 factors are needed to account for its higher-order structure.

Development and validation of the Schedule for Nonadaptive and Adaptive Personality Brief Self-Description Rating Form (SNAP-BSRF).

The Schedule for Nonadaptive and Adaptive Personality full-length (SNAP) and short versions (SNAP-SRF and SNAP-ORF) were developed as measures of normal-range and more pathological personality traits. This study investigated the validity of the SNAP Brief Self-Description Rating Form (SNAP-BSRF), an alternative version of the SNAP Self-Description Rating Form (SNAP-SRF) revised for further brevity. The scales of the SNAP-BSRF showed good convergence with the SNAP-SRF and the SNAP Other-Description Rating Form (SNAP-ORF) scales. A three-factor structure consistent with extant literature was found for the SNAP-BSRF using an exploratory structural equation modeling approach. Scales from the SNAP-BSRF showed meaningful associations with self-reported internalizing symptoms. Results suggest that this new version is a reasonable substitute for the SNAP-SRF and will be useful when a very brief measure of adaptive and maladaptive personality is needed.

Longitudinal Associations Between Reactive and Regulatory Temperament Traits and Depressive Symptoms in Middle Childhood.

Although a large literature has examined the role of temperament in adult and adolescent depression, few studies have investigated interactions between reactive and regulatory temperament traits in shaping depressive symptoms in children over time. Child temperament measures (laboratory observations and maternal reports) and depressive symptoms were collected from 205 seven-year-olds (46% boys), who were followed up 1 (N=181) and 2 (N=171) years later. Child participants were Caucasian (87.80%), Asian (1.95%), or other ethnicity (7.80%); 2.45% of the sample was missing ethnicity data. Multilevel modeling was used to investigate within- and between-person variance in intercepts and slopes of child depressive symptoms. A steeper increase in depressive symptoms was found for children lower in laboratory-assessed effortful control (EC). Lower mother-reported surgency and higher mother-reported NE predicted increases in child depressive symptoms in the context of lower mother-reported EC. Our findings implicate EC as having main and moderating effects related to depressive symptoms in middle childhood. We emphasize the importance of developing prevention programs that enhance EC-like abilities.

Child temperament and parental depression predict cortisol reactivity to stress in middle childhood.

Children's cortisol reactivity to stress is an important mediator of depression risk, making the search for predictors of such reactivity an important goal for psychopathologists. Multiple studies have linked maternal depression and childhood behavioral inhibition (BI) independently to child cortisol reactivity, yet few have tested multivariate models of these risks. Further, paternal depression and other child temperament traits, such as positive emotionality (PE), have been largely ignored despite their potential relevance. We therefore examined longitudinal associations between child fear/BI and PE and parental depression, and children's cortisol stress reactivity, in 205 7-year-olds. Paternal depression and child fear/BI predicted greater cortisol stress reactivity at a follow-up of 164 9-year-olds, and maternal depression and child PE interacted to predict children's cortisol reactivity, such that higher child PE predicted lower cortisol reactivity in the context of maternal depression. Results highlight the importance of both parents' depression, as well as multiple facets of child temperament, in developing more comprehensive models of childhood cortisol reactivity to stress.

Structure of observed temperament in middle childhood.

Although much is known about the structure of adult temperament and personality, significantly less is known about the structure of child temperament. We examined the structure of child temperament in 205 seven-year-olds using observational measures. Exploratory factor analysis identified factors representing positive emotionality/sociability, disinhibition/anger, fear/behavioral inhibition, and sadness. The predictive validity of these dimensions was evaluated by examining their associations with children's internalizing and externalizing symptoms: positive emotionality/sociability showed positive associations with ADHD symptoms, disinhibition/anger showed positive associations with externalizing symptoms, fear/behavioral inhibition showed negative associations with ADHD and CD symptoms, and sadness showed positive associations with both internalizing and externalizing problems. These associations were consistent with extant literature on temperament and psychopathology, supporting the validity of the structure obtained.