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1.
Sensors (Basel) ; 24(4)2024 Feb 08.
Article in English | MEDLINE | ID: mdl-38400277

ABSTRACT

Fog computing is today considered a promising candidate to improve the user experience in dynamic on-demand computing services. However, its ubiquitous application would require support for this service in wireless multi-hop mesh systems, where the use of conventional IP-based solutions is challenging. As a complementary solution, in this paper, we consider a Named-Data Networking (NDN) approach to enable fog computing services in autonomous dynamic mesh formations. In particular, we jointly implement two critical mechanisms required to extend the NDN-based fog computing architecture to wireless mesh systems. These are (i) dynamic face management systems and (ii) a learning-based route discovery strategy. The former makes it possible to solve NDN issues related to an inability to operate over a broadcast medium. Also, it improves the data-link layer reliability by enabling unicast communications between mesh nodes. The learning-based forwarding strategy, on the other hand, efficiently reduces the amount of overhead needed to find routes in the dynamically changing mesh networks. Our numerical results show that, for static wireless meshes, our proposal makes it possible to fully benefit from the computing resources sporadically available up to several hops away from the consumer. Additionally, we investigate the impacts of various traffic types and NDN caching capabilities, revealing that the latter result in much better system performance while the popularity of the compute service contributes to additional performance gains.

2.
Sensors (Basel) ; 21(11)2021 Jun 03.
Article in English | MEDLINE | ID: mdl-34205190

ABSTRACT

Automated systems have been seamlessly integrated into several industries as part of their industrial automation processes. Employing automated systems, such as autonomous vehicles, allows industries to increase productivity, benefit from a wide range of technologies and capabilities, and improve workplace safety. So far, most of the existing systems consider utilizing one type of autonomous vehicle. In this work, we propose a collaboration of different types of unmanned vehicles in maritime offshore scenarios. Providing high capacity, extended coverage, and better quality of services, autonomous collaborative systems can enable emerging maritime use cases, such as remote monitoring and navigation assistance. Motivated by these potential benefits, we propose the deployment of an Unmanned Surface Vehicle (USV) and an Unmanned Aerial Vehicle (UAV) in an autonomous collaborative communication system. Specifically, we design high-speed, directional communication links between a terrestrial control station and the two unmanned vehicles. Using measurement and simulation results, we evaluate the performance of the designed links in different communication scenarios and we show the benefits of employing multiple autonomous vehicles in the proposed communication system.

3.
Sensors (Basel) ; 22(1)2021 Dec 24.
Article in English | MEDLINE | ID: mdl-35009652

ABSTRACT

Cloud Computing and Cloud Platforms have become an essential resource for businesses, due to their advanced capabilities, performance, and functionalities. Data redundancy, scalability, and security, are among the key features offered by cloud platforms. Location-Based Services (LBS) often exploit cloud platforms to host positioning and localisation systems. This paper introduces a systematic review of current positioning platforms for GNSS-denied scenarios. We have undertaken a comprehensive analysis of each component of the positioning and localisation systems, including techniques, protocols, standards, and cloud services used in the state-of-the-art deployments. Furthermore, this paper identifies the limitations of existing solutions, outlining shortcomings in areas that are rarely subjected to scrutiny in existing reviews of indoor positioning, such as computing paradigms, privacy, and fault tolerance. We then examine contributions in the areas of efficient computation, interoperability, positioning, and localisation. Finally, we provide a brief discussion concerning the challenges for cloud platforms based on GNSS-denied scenarios.

4.
Sensors (Basel) ; 20(14)2020 Jul 12.
Article in English | MEDLINE | ID: mdl-32664617

ABSTRACT

Dynamic blockage of radio propagation paths between the user equipment (UE) and the 5G New Radio (NR) Base Station (BS) induces abrupt rate fluctuations that may lead to sub-optimal performance of the Transmission Control Protocol (TCP) protocol. In this work, we characterize the effects of dynamic human blockage on TCP throughput at the 5G NR air interface. To this aim, we develop an analytical model that expresses the TCP throughput as a function of the round-trip time (RTT), environmental, and radio system parameters. Our results indicate that the blockage affects TCP throughput only when the RTT is comparable to the blocked and non-blocked state durations when the frequency of state changes is high. However, such conditions are not typical for dynamic body blockage environments allowing TCP to benefit from the high bandwidth of 5G NR systems fully.


Subject(s)
Human Body , Radio Waves , Humans
5.
Sensors (Basel) ; 20(12)2020 Jun 13.
Article in English | MEDLINE | ID: mdl-32545719

ABSTRACT

The present increase of attention toward blockchain-based systems is currently reaching a tipping point with the corporate focus shifting from exploring the technology potential to creating Distributed Ledger Technology (DLT)-based systems. In light of a significant number of already existing blockchain applications driven by the Internet of Things (IoT) evolution, the developers are still facing a lack of tools and instruments for appropriate and efficient performance evaluation and behavior observation of different blockchain architectures. This paper aims at providing a systematic review of current blockchain evaluation approaches and at identifying the corresponding utilization challenges and limitations. First, we outline the main metrics related to the blockchain evaluation. Second, we propose the blockchain modeling and analysis classification based on the critical literature review. Third, we extend the review with publicly accessible industrial tools. Next, we analyze the selected results for each of the proposed classes and outline the corresponding limitations. Finally, we identify current challenges of the blockchain analysis from the system evaluation perspective, as well as provide future perspectives.

6.
IEEE Trans Nanobioscience ; 19(2): 224-236, 2020 04.
Article in English | MEDLINE | ID: mdl-32092011

ABSTRACT

With the advancement of synthetic biology, several new tools have been conceptualized over the years as alternative treatments for current medical procedures. As part of this work, we investigate how synthetically engineered neurons can operate as digital logic gates that can be used towards bio-computing inside the brain and its impact on epileptic seizure-like behaviour. We quantify the accuracy of logic gates under high firing rates amid a network of neurons and by how much it can smooth out uncontrolled neuronal firings. To test the efficacy of our method, simulations composed of computational models of neurons connected in a structure that represents a logic gate are performed. Our simulations demonstrate the accuracy of performing the correct logic operation, and how specific properties such as the firing rate can play an important role in the accuracy. As part of the analysis, the mean squared error is used to quantify the quality of our proposed model and predict the accurate operation of a gate based on different sampling frequencies. As an application, the logic gates were used to smooth out epileptic seizure-like activity in a biological neuronal network, where the results demonstrated the effectiveness of reducing its mean firing rate. Our proposed system has the potential to be used in future approaches to treating neurological conditions in the brain.


Subject(s)
Computers, Molecular , Models, Neurological , Neurons , Synthetic Biology/methods , Brain/physiology , Epilepsy/physiopathology , Humans , Logic , Nanotechnology , Neurons/cytology , Neurons/physiology
7.
Sensors (Basel) ; 19(7)2019 Apr 03.
Article in English | MEDLINE | ID: mdl-30987097

ABSTRACT

Today, the Intelligent Transportation Systems (ITS) are already in deep integration phase all over the world. One of the most significant enablers for ITS are vehicle positioning and tracking techniques. Worldwide integration of ITS employing Dedicated Short Range Communications (DSRC) and European standard for vehicular communication, known as ETSI ITS-G5, brings a variety of options to improve the positioning in areas where GPS connectivity is lacking precision. Utilization of the ready infrastructure, next-generation cellular 5G networks, and surrounding electronic devices together with conventional positioning techniques could become the solution to improve the overall ITS operation in vehicle-to-everything (V2X) communication scenario. Nonetheless, effective and secure communication protocols between the vehicle and roadside units should be both analyzed and improved in terms of potential attacks on the transmitted positioning-related data. In particular, said information might be misused or stolen at the infrastructure side conventionally assumed to be trusted. In this paper, we first survey different methods of vehicle positioning, which is followed by an overview of potential attacks on ITS systems. Next, we propose potential improvements allowing mutual authentication between the vehicle and infrastructure aiming at improving positioning data privacy. Finally, we propose a vision on the development and standardization aspects of such systems.

8.
IEEE Trans Nanobioscience ; 16(8): 859-872, 2017 12.
Article in English | MEDLINE | ID: mdl-29364130

ABSTRACT

In recent years, numerous research efforts have been dedicated toward developing efficient implantable devices for brain stimulation. However, there are limitations and challenges with the current technologies. They include neuron population stimulation instead of single neuron level, the size, the biocompatibility, and the device lifetime reliability in the patient's brain. We have recently proposed the concept of wireless optogenetic nanonetworking devices (WiOptND) that could address the problem of long term deployment, and at the same time target single neuron stimulation utilizing ultrasonic as a mode for energy harvesting. In addition, a number of charging protocols are also proposed, in order to minimize the quantity of energy required for charging, while ensuring minimum number of neural spike misfirings. These protocols include the simple charge and fire, which requires the full knowledge of the raster plots of neuron firing patterns, and the predictive sliding detection window, and its variant Markov-chain based time-delay patterns, which minimizes the need for full knowledge of neural spiking patterns as well as number of ultrasound charging frequencies. Simulation results exhibit a drop for the stimulation ratio of ~ 25% and more stable trend in its efficiency ratio (standard deviation of ~0.5%) for the Markov-chain based time-delay patterns protocol compared with the baseline change and fire. The results show the feasibility of utilizing WiOptND for long-term implants in the brain, and a new direction toward precise stimulation of neurons in the cortical microcolumn of the brain cortex.


Subject(s)
Brain/physiology , Computers, Molecular , Electric Stimulation Therapy , Neural Prostheses , Optogenetics , Wireless Technology , Action Potentials/physiology , Humans , Prosthesis Design
9.
IEEE Trans Nanobioscience ; 15(5): 488-498, 2016 07.
Article in English | MEDLINE | ID: mdl-27514062

ABSTRACT

The use of intra/inter-cellular calcium ion (Ca2+) signaling for molecular communication (MC) is investigated in this paper. In particular, the elevation of the intracellular Ca2+ concentration upon the external excitation, i.e., Ca2+ wave generation, and the intercellular propagation of Ca2+ wave over consecutive cells are studied for information transmission. The main objective of this paper is to develop a linear channel model for intra/inter-cellular Ca2+ MC. In this context, the end-to-end Ca2+ MC system is studied under three blocks: the wave generation, the gap junctional (intercellular) propagation, and the intracellular propagation. The wave generation block captures the intracellular Ca2+ signaling pathway including the release of Ca2+ from the organelles and the buffers inside a cell, and the intake from the extracellular space. The gap junctional (intercellular) propagation block captures the Ca2+ transition through the gap junctions between the touching cells. The intracellular propagation block defines the effect of the cytoplasmic diffusion. Using the developed blocks for the different biophysical phenomena, the end-to-end channel gain and delay formulas are derived. Furthermore, the bit error probability is studied to reveal the impact of the detection threshold. This work provides the basis for the modeling, analysis and the design of Ca2+ MC systems.


Subject(s)
Calcium Signaling/physiology , Cell Communication/physiology , Computational Biology/methods , Computers, Molecular , Models, Biological
10.
IEEE Trans Biomed Eng ; 62(7): 1683-95, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25675450

ABSTRACT

Antibody-mediated Drug Delivery Systems (ADDS) are emerging as one of the most encouraging therapeutic solutions for treating several diseases such as human cancers. ADDS use small molecules (antibodies) that propagate in the body and bind selectively to their corresponding receptors (antigens) expressed at the surface of the diseased cells. In this paper, the Molecular Communication (MC) paradigm, where information is conveyed through the concentration of molecules, is advocated for the engineering of ADDS and modeling their complex behavior, to provide a realistic model without the over-complication of system biology models, and the limitations of experimental approaches. The peculiarities of antibodies, including their anisotropic transport and complex electrochemical structure, are taken into account to develop an analytical model of the ADDS transport and antigen-binding kinetics. The end-to-end response of ADDS, from the drug injection to the drug absorption, is mathematically derived based on the geometry of the antibody molecule, the electrochemical structure of the antibody-antigen complex, and the physiology of the patient. The accuracy of the MC model is validated by finite-element (COMSOL) simulations. The implications of the complex interplay between the transport and kinetics parameters on the performance of ADDS are effectively captured by the proposed MC model. The MC model of ADDS will enable the discovery and optimization of drugs in a versatile, cost-efficient, and reliable manner.


Subject(s)
Antibodies/metabolism , Drug Delivery Systems , Models, Biological , Models, Molecular , Blood Vessels/physiology , Computer Simulation , Finite Element Analysis , Humans , Immunoconjugates , Pharmacokinetics
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