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1.
J Cutan Pathol ; 28(6): 303-6, 2001 Jul.
Article in English | MEDLINE | ID: mdl-11401677

ABSTRACT

BACKGROUND: Volar melanotic macules are asymptomatic light-brown or tannish-grey macules usually found on the palms and/or soles of blacks, although they have also been reported on the volar surfaces of whites. Similar lesions have not been reported before in Japanese people. Since the cause is as yet unknown, it remains to be discussed whether they are a distinct entity. METHODS: In this report, a 52-year-old Japanese man with volar melanotic macules is reported with the clinical and histopathological findings. RESULTS: A 52-year-old Japanese man presented with many light-brown macules on his bilateral soles. He had a 20-year history of tinea pedis. Histopathological examination revealed melanophages and inflammatory infiltrates in the superficial dermis. There was a slight increase in melanin granules around the acrosyringium. Fontana-Masson stain revealed a slight increase in melanin granules in the basal layer including the acrosyringium and superficial dermis. These changes corresponded with postinflammatory pigmentation. CONCLUSIONS: This is the first report of volar melanotic macules in Japanese people. We suggest that volar melanotic macules is not an independent entity but a clinicopathological one that includes postinflammatory pigmentation, and that the condition is the volar counterpart of mucosal melanotic macules.


Subject(s)
Foot Dermatoses/pathology , Melanosis/pathology , Skin/pathology , Foot/pathology , Foot Dermatoses/complications , Foot Dermatoses/metabolism , Humans , Male , Melanins/metabolism , Melanosis/complications , Melanosis/metabolism , Middle Aged
2.
J Dermatol ; 24(10): 670-4, 1997 Oct.
Article in English | MEDLINE | ID: mdl-9375468

ABSTRACT

Congenital ectopic nails are quite unusual and characterized by development of nail-like tissue on the tips of one or more fingers. We present the case of a boy with congenital ectopic nails on both little fingers. To prevent tapering of the fingertips following surgery, we used subcutaneous pedicle flaps and obtained a satisfactory cosmetic result.


Subject(s)
Choristoma/congenital , Choristoma/surgery , Fingers/surgery , Nails , Plastic Surgery Procedures/methods , Skin Transplantation , Surgical Flaps , Choristoma/pathology , Fingers/pathology , Humans , Infant, Newborn , Male
3.
Jpn J Antibiot ; 50(1): 39-44, 1997 Jan.
Article in Japanese | MEDLINE | ID: mdl-9059912

ABSTRACT

The clinical efficacy was evaluated on 1% silver sulfadiazine (AgSD) cream (Geben cream) for the treatment of ulcerative skin lesions infected with MRSA (methicillin-resistant Staphylococcus aureus). 1% AgSD cream was applied once a day to cutaneous ulcers such as burns or decubitus or various other ulcers, infected with MRSA, in 13 patients. MRSA was eradicated in 45.5% of 11 evaluable patients. The clinical efficacy rate of 1% AgSD cream was 72.7% in this series of treatment. No side effects were noted in any of the patients, either locally or systemically. The results of the present study have indicated that 1% AgSD cream is useful for cutaneous ulcers such as burns or decubitus, infected with MRSA.


Subject(s)
Anti-Infective Agents, Local/administration & dosage , Silver Sulfadiazine/administration & dosage , Skin Diseases, Bacterial/drug therapy , Skin Ulcer/drug therapy , Staphylococcal Infections/drug therapy , Administration, Topical , Adult , Aged , Female , Humans , Male , Methicillin Resistance , Middle Aged , Ointments , Skin Diseases, Bacterial/microbiology , Skin Ulcer/microbiology , Staphylococcal Infections/microbiology , Staphylococcus aureus/isolation & purification
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