ABSTRACT
La alergia al látex es un problema creciente en las últimas décadas. El objetivo del presente estudio fue caracterizar la prevalencia de sensibilidadal látex y a los aditivos de la goma en el personal de salud del Hospital Universitario de Caracas que acude a la consulta de Dermatitis de Contactodel Servicio de Dermatología. Se realiza un estudio descriptivo de corte transversal y prospectivo, se incluyeron 43 pacientes con clínica dermatitisde contacto de las manos posterior a la exposición a los guantes de látex, se evaluaron características epidemiológicas, clínicas y la respuestaa las pruebas cutáneas específicas.De 43 pacientes, 23 sujetos (53%) presentaban prueba de prick test positiva para látex y 8 (18,6%) tenían prueba de patch test positivo para losaditivos de la goma. La media de edad 36 años. La mayoría femenino. No se encontró diferencias estadísticamente significativas entre los antecedentespersonales y familiares de atopia y la respuesta a las pruebas cutáneas. La reactividad al látex se correlaciona con la dermatitis de contactoen las manos presente antes o durante la exposición. La mezcla de Carba y Tiuram fueron los aditivos de la goma más encontrados. La principalfuente de sensibilización son lo guantes por lo que el conocimiento sobre la prevención y sustitutos del material deben ser conocidos, para definirestrategias para su control (AU)
The latex allergy is an increasing problem in the last decades. The objective of the present study was to characterize the prevalence of sensitivityto the latex and additives of the rubber in the personnel of health of the University Hospital of Caracas that goes to the consultation of ContactDermatitis of the Department of Dermatology. A descriptive cross section and prospective was performed study , including 43 patients with clinicalcontact dermatitis of the hands exposed to the latex gloves, evaluated were. Epidemiology, clinical aspects and results to the specific cutaneoustests.Twenty three (53%) out of 43 patients positive prick test for latex and 8 (18.6%) had positive patch test for additives of the rubber. The age averagewas 36 years. Mainly females was not statistically significant differences between the personal and familiar antecedents of atopia and theanswer to the cutaneous tests. The reactivity to the latex were correlated with the contact dermatitis hands of presents before or during the exposition.The Carba and Tiuram mix was the additives of the rubber more mainly found. The main source of sensitivity was the gloves by which theknowledge on the prevention and substitutes of that material must be known, to define strategies for its control (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Latex Hypersensitivity/epidemiology , Latex Hypersensitivity/diagnosis , Personnel, Hospital/statistics & numerical data , Hospitals, University , Cross-Sectional Studies , Prospective Studies , Skin Tests , VenezuelaABSTRACT
The clinical course is described of two genuine cases of the disease of Leber's miliary aneurysms that developed into Coats' disease. Following the issue of the disease in a painful and blind eye, the cases were examined histopathologically. In the first case the transformation into Coats' disease, and subsequently into a painful eye, took six years, in the second case four years. This histopathological examination revealed vascular formations of the superficial corneal stroma of the periphery in the second case. In respect of the retina the presence of neovascularization was observed. Pathological vessels of varying width were also found in the deeper retinal layers. The presence of cholesterol clefts should be regarded rather as a consequence of the chronicity of the case than as being a characteristic feature of the condition.
