[Resistance to antibiotics used in Helicobacter pylori infection in children]. / Opornosc na antybiotyki stosowane w zakazeniu Helicobacter pylori u dzieci.

In literature and clinical findings, the attention has been turned to the resistance to the antibiotics used in Helicobacter pylori eradication, especially metronidazole and clarithromycin. Drug-resistance was evaluated in 50 children. Primary drug-resistance to the antibiotics used in eradications was determined in this group, and additionally, in 18 children who were subjected twice to unsuccessful eradicative therapy. The highest secondary resistance to metronidazole up to 72.0% was found among conventionally used antibiotics. Primary resistance of H. pylori rods to clarithromycin was also high and equaled 25.0%. However, in our study secondary resistance to macrolides was about 66.0%. In our study combined primary resistance to clarithromycin and metronidazole was about 7.2%. There was not H. pylori rods resistance to amoxicillin and tetracyclines.

[Clinical picture and morphological changes of upper intestinal tract mucosa in children with Helicobacter pylori infection]. / Obraz kliniczny i zmiany morfologiczne blony sluzowej górnego odcinka przewodu pokarmowego u dzieci zakazonych Helicobacter pylori.

The authors analysed clinical picture and morphological (macroscopic and histopathologic) changes in gastric and duodenal mucosa in 150 children diagnosed with Helicobacter pylori infection chosen randomly among the hospitalized in 1998-2000 years.